Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.330 Biomarker group BEFREE Thus RAF1, although essential for the development of skin and lung tumours, is a negative regulator of hepatocarcinogenesis. 28000790 2016
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.330 Biomarker group BEFREE Elimination of B-RAF in oncogenic C-RAF-expressing alveolar epithelial type II cells reduces MAPK signal intensity and lung tumor growth. 25096573 2014
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.330 AlteredExpression group BEFREE Whereas expression of oncogenic C-RAF in alveolar type II cells readily induced multifocal macroscopic lung tumors independent of the developmental state, few tumors with type II pneumocytes features and incomplete penetrance were found when targeted to Clara cells. 22131876 2011
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.330 Biomarker group CTD_human Levels of K-ras p21, raf-1, mitogen-activated protein kinases Erk 1 and 2, the phosphorylated-activated forms of Erk 1 and 2 (Erk 1P and 2P), and proliferating cell nuclear antigen (PCNA) were measured by immunoblotting in mouse lung tumors (5 to 9 mm in size) caused by N-nitrosodimethylamine (NDMA) and in control lungs. 11884234 2002