Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.330 GeneticVariation group BEFREE Application of these signatures to breast tumor gene expression data identified two novel discrete phenotypes characterized by concordant, aberrant activation of either the HER2, IGF1R, and AKT pathways ("the survival phenotype") or the EGFR, KRAS (G12V), RAF1, and BAD pathways ("the growth phenotype"). 28446242 2017
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.330 AlteredExpression group BEFREE EZH2 promotes expansion of breast tumor initiating cells through activation of RAF1-β-catenin signaling. 21215703 2011
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.330 Therapeutic group CTD_human The effects of beta-estradiol on Raf activity, cell cycle progression and growth factor synthesis in the MCF-7 breast cancer cell line. 12432273 2003
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.330 GeneticVariation group BEFREE The shortest region of homozygosity in primary human breast tumor is located between the DNF15S2 and RAF1 loci in the 3p21-p25 region on the short arm of chromosome 3. 2573734 1989