RB1, RB transcriptional corepressor 1, 5925

N. diseases: 339; N. variants: 239
Disease: Endometrial Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.050 AlteredExpression disease BEFREE In summary, our findings indicate a mechanism by which PRB can promote cell survival in the setting of high AKT activity in endometrial cancer cells. 21760855 2011
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.050 Biomarker disease BEFREE The possible role of specific progesterone receptor (PR) isoforms (PRA and PRB) as predictive factors in endometrial carcinoma is unclear. 16999816 2006
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.050 Biomarker disease BEFREE This study aimed to investigate the mechanism of action of progesterone and the loss of its receptors (PRA and PRB) in development of endometrial cancer. 14519645 2003
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.050 AlteredExpression disease BEFREE Our MSP and direct DNA sequencing showed that ERalpha-A, ERalpha-B, and PR-A genes were unmethylated and ERalpha-C and PR-B were methylated in endometrial cancers although ERalpha-A and ERalpha-B were methylated and ERalpha-C, PRA and PRB were unmethylated in prostate cancers. 12770752 2003
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.050 PosttranslationalModification disease BEFREE To determine the methylation status of PRB in UEC patients, we investigated 83 cancerous and 33 normal samples. 11196205 2001