MAPK signaling pathway, NF‑kappa B signaling pathway, and Toll‑like receptor signaling pathway were involved in LDABS‑mediated liver regeneration, with Retinoblastoma 1 (Rb1), Cyclin D1, Cyclin‑dependent kinase 4, Mitogen‑activated protein kinase 10 (Mapk10) and CAMP responsive element binding protein 1 genes in the initiation phase, Kirsten rat sarcoma viral oncogene homolog (Kras), tumor protein 53, MYC proto‑oncogene, BHLH transcription factor, Cyclin E1 and Heat shock protein family B (small) member 1 genes in the proliferation phase, Kras, Rb1, Jun proto‑oncogene, AP‑1 transcription factor subunit, Cyclin D2 and Mapk10 genes in the termination phase were identified as key genes in LDABS‑mediated liver regeneration using MAPK signaling PCR array analysis.