REN, renin, 5972

N. diseases: 721; N. variants: 25
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver
0.360 Biomarker disease BEFREE The renin-angiotensin system (RAS) has a substantial role in liver fibrosis, cirrhosis, and portal hypertension. 31348596 2019
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver
0.360 GeneticVariation disease BEFREE We have recently shown that liver-specific over-expression of angiotensin converting enzyme 2 (ACE2) of the renin angiotensin system (RAS) ameliorated liver fibrosis in mice. 29977014 2018
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver
0.360 Biomarker disease BEFREE Renin-angiotensin system (RAS) seems to contribute to the development of hepatic fibrosis. 29425464 2018
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver
0.360 Biomarker disease BEFREE Periostin cross‑reacts with the renin‑angiotensin system during liver fibrosis development. 28849131 2017
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver
0.360 Biomarker disease BEFREE The RAS (renin-angiotensin system) is now recognized as an important regulator of liver fibrosis and portal pressure. 22548407 2012
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver
0.360 Biomarker disease BEFREE Experimental evidence and clinical studies suggest that the renin-angiotensin system and its inhibitors may play a role in regulating the mechanisms of liver fibrosis development. 17653650 2007
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver
0.360 Biomarker disease CTD_human Inhibition of cGMP-specific phosphodiesterase type 5 reduces sodium excretion and arterial blood pressure in patients with NaCl retention and ascites. 15613622 2005