RGR, retinal G protein coupled receptor, 5995

N. diseases: 43; N. variants: 5
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1862475
Disease: Abnormality of retinal pigmentation
Abnormality of retinal pigmentation
0.100 Biomarker phenotype HPO
CUI: C0242383
Disease: Age related macular degeneration
Age related macular degeneration
0.010 Biomarker disease BEFREE In Western blot assays, the RGR-d protein was detected in retinas of a large proportion ( approximately 53%) of individual donors, including patients with age-related macular degeneration (AMD). 16530760 2006
CUI: C1840077
Disease: Anteverted nostril
Anteverted nostril
0.100 Biomarker phenotype HPO
Attenuation of retinal blood vessels
0.100 Biomarker phenotype HPO
CUI: C4021786
Disease: Atypical scarring of skin
Atypical scarring of skin
0.100 Biomarker phenotype HPO
CUI: C0456909
Disease: Blindness
Blindness
0.100 Biomarker phenotype HPO
CUI: C0086543
Disease: Cataract
Cataract
0.100 Biomarker disease HPO
CUI: C0018777
Disease: Conductive hearing loss
Conductive hearing loss
0.100 Biomarker disease HPO
CUI: C0266435
Disease: Congenital hypoplasia of penis
Congenital hypoplasia of penis
0.100 Biomarker disease HPO
Decreased light- and dark-adapted electroretinogram amplitude
0.100 Biomarker phenotype HPO
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease HPO
CUI: C0015397
Disease: Disorder of eye
Disorder of eye
0.300 Biomarker group GENOMICS_ENGLAND
CUI: C0015397
Disease: Disorder of eye
Disorder of eye
0.300 Biomarker group GENOMICS_ENGLAND
CUI: C0015397
Disease: Disorder of eye
Disorder of eye
0.300 Biomarker group GENOMICS_ENGLAND
CUI: C1260959
Disease: Drusen
Drusen
0.010 Biomarker disease BEFREE RGR-d was analyzed in drusen and Bruch's membrane by immunohistochemical localization. 19450444 2009
CUI: C1282983
Disease: ehrlichiosis chafeensis (diagnosis)
ehrlichiosis chafeensis (diagnosis)
0.010 Biomarker disease BEFREE Neither human anti-Ehrlichia chaffeensis serum nor rabbit anti-Borrelia burgdorferi serum reacted with rP44. 9620397 1998
CUI: C0476397
Disease: Electroretinogram abnormal
Electroretinogram abnormal
0.100 Biomarker phenotype HPO
CUI: C0017601
Disease: Glaucoma
Glaucoma
0.100 Biomarker disease HPO
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
0.010 Biomarker disease BEFREE Furthermore, CGKRK and RGR peptides strongly bound to blood vessels in freshly resected human GBM, demonstrating shared peptide-binding activities in mouse and human primary brain tumour vessels. 29603739 2018
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme
0.010 Biomarker disease BEFREE Furthermore, CGKRK and RGR peptides strongly bound to blood vessels in freshly resected human GBM, demonstrating shared peptide-binding activities in mouse and human primary brain tumour vessels. 29603739 2018
Human anaplasmosis due to Anaplasma phagocytophilum
0.030 Biomarker disease BEFREE Therefore, Western immunoblot analysis using rP44 and rP30 may be useful in discriminating dually HME and HGE IFA-reactive sera. 11682518 2001
Human anaplasmosis due to Anaplasma phagocytophilum
0.030 Biomarker disease BEFREE This suggests that rP44 is an HGE-E. equi group-specific antigen. 9620397 1998
Human anaplasmosis due to Anaplasma phagocytophilum
0.030 Biomarker disease BEFREE Proteinase K treatment of the HGE agent or rP44 eliminated the ability to induce these three cytokines. 10816490 2000
CUI: C0020459
Disease: Hyperinsulinism
Hyperinsulinism
0.100 Biomarker disease HPO
CUI: C0151889
Disease: Hyperreflexia
Hyperreflexia
0.100 Biomarker phenotype HPO