BCL6, BCL6 transcription repressor, 604

N. diseases: 309; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024302
Disease: Reticulosarcoma
Reticulosarcoma
0.320 Biomarker disease CTD_human Suppression of human B cell activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin involves altered regulation of B cell lymphoma-6. 25543051 2015
CUI: C0024302
Disease: Reticulosarcoma
Reticulosarcoma
0.320 AlteredExpression disease BEFREE In the presence of EBV infection, BCL-6 expressing AIDS-LCL fails to express the latent membrane protein 1 (LMP1) antigen. 12055673 2002
CUI: C0024302
Disease: Reticulosarcoma
Reticulosarcoma
0.320 GeneticVariation disease BEFREE This study suggests that BCL6 rearrangement is primarily associated with large cell lymphoma, and that BCL2(-)BCL6(+) NHL could potentially be curable with modern combination chemotherapy. 9209377 1997