RNF6, ring finger protein 6, 6049

N. diseases: 46; N. variants: 4
Disease: leukemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023418
Disease: leukemia
leukemia 		0.020 Biomarker disease BEFREE Ring finger protein 6 (RNF6) is a key oncogene in both prostate cancer and leukemia, but its role is elusive in breast cancer. 28223545 2017
CUI: C0023418
Disease: leukemia
leukemia 		0.020 Biomarker disease BEFREE This study thus suggests that RNF6 overexpression in leukemia is under the direction of PBX1 and that the PBX1/RNF6 axis can be developed as a novel therapeutic target of leukemia. 26971355 2016