RORC, RAR related orphan receptor C, 6097

N. diseases: 88; N. variants: 6
Disease: Diabetes ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011847
Disease: Diabetes
Diabetes 		0.040 Biomarker disease BEFREE TOR conservation from flies to humans indicates that probiotic therapy with L. fermentum NCIMB 5221 has a high therapeutic potential towards several human energy regulatory diseases such as obesity, diabetes and cancer. 30368647 2019
CUI: C0011847
Disease: Diabetes
Diabetes 		0.040 AlteredExpression disease BEFREE In-Vitro Analysis of Glucose and Quercetin Effects on m-TOR and Nrf-2 Expression in HepG2 Cell Line (Diabetes and Cancer Connection). 29781726 2018
CUI: C0011847
Disease: Diabetes
Diabetes 		0.040 Biomarker disease BEFREE TOR is a master regulator of the cell's growth and metabolic state, and its dysregulation contributes to a variety of diseases, including diabetes, obesity, neurodegenerative disorders, aging, and cancer, making the TOR pathway an attractive therapeutic target. 28888322 2017
CUI: C0011847
Disease: Diabetes
Diabetes 		0.040 Biomarker disease BEFREE MicroRNA-21 orchestrates high glucose-induced signals to TOR complex 1, resulting in renal cell pathology in diabetes. 21613227 2011