melanoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
The RPL8 antigen may represent a relevant vaccine target for patients with melanoma, glioma, and breast carcinoma whose tumors express this protein.
|
17440064 |
2007 |
Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
The RPL8 antigen may represent a relevant vaccine target for patients with melanoma, glioma, and breast carcinoma whose tumors express this protein.
|
17440064 |
2007 |
Breast Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
The RPL8 antigen may represent a relevant vaccine target for patients with melanoma, glioma, and breast carcinoma whose tumors express this protein.
|
17440064 |
2007 |
Liver carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
In addition to the overexpression of AFP, these genes (increased in the presence of HCC) are involved in many processes, such as transcription and protein biosynthesis (HNRPDL, PABPC1, POLR2K, SRP9, SNRPA, and six ribosomal protein genes including RPL8, RPL14, RPL41, RPS5, RPS17, RPS24), the metabolism of lipids and proteins (FADS1, ApoA-II, ApoM, FTL), cell proliferation (Syndecan-2, and Annexin A2), and signal transduction (LRRC28 and FMR1).
|
17786358 |
2007 |
Glioblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Further, the most significant module consisted of 28 downregulated proteins that were filtered from the PPI network, and 9 proteins (DHX9, HNRNPR, RPL3, HNRNPA3, SF1, DDX5, EIF5B, BTF3, and RPL8) among them were identified as the key candidate proteins, which were significantly associated with prognosis of GBM patients and mainly involved in ribosome and spliceosome pathway.
|
29687002 |
2018 |
Glioblastoma Multiforme
|
0.010 |
Biomarker
|
disease |
BEFREE |
Further, the most significant module consisted of 28 downregulated proteins that were filtered from the PPI network, and 9 proteins (DHX9, HNRNPR, RPL3, HNRNPA3, SF1, DDX5, EIF5B, BTF3, and RPL8) among them were identified as the key candidate proteins, which were significantly associated with prognosis of GBM patients and mainly involved in ribosome and spliceosome pathway.
|
29687002 |
2018 |