Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027765
Disease: nervous system disorder
nervous system disorder
0.010 GeneticVariation group BEFREE Studies must have described the planning/implementation of BCS targeting PA in adults with neurological disorders, with interventions delivered by a HCP. 30496560 2020
Diabetes Mellitus, Non-Insulin-Dependent
0.010 Biomarker disease BEFREE Drug delivery and therapeutic challenges of gliclazide, a BCS class II drug used in type 2 diabetes mellitus (T2DM) can be overcome by exploring smarter carriers of second-generation nanocrystals (SGNCs). 31758056 2019
CUI: C0015672
Disease: Fatigue
Fatigue
0.010 Biomarker phenotype BEFREE <b>Conclusion:</b> Our results suggest that BCS1L and complex III in mitochondrial mononuclear cells are potential biomarkers and feasible therapeutic targets for acute XRT-induced fatigue in this clinical population. 31410061 2019
CUI: C0238031
Disease: Breast Phyllodes Tumor
Breast Phyllodes Tumor
0.010 GeneticVariation disease BEFREE We recommend application of ART for such patients but the role of ART in patients with borderline and malignant PTB treated with BCS and with surgical margin < 1 cm remains uncertain. 30521986 2019
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.010 Biomarker disease BEFREE Among women with DCIS, those at risk for MDD were more likely to receive BCS (adjusted odds ratio [AOR] 2.04, 95% CI 1.04-4.00, p = 0.04) or mastectomy (AOR 1.88, 95% CI 0.91-3.86, p = 0.09) compared to BCS + RT. 30406869 2019
CUI: C0001956
Disease: Alcohol Use Disorder
Alcohol Use Disorder
0.010 Biomarker disease BEFREE This study attempted to devise a brief cognitive screen (BCS- AUD) for alcohol use disorders. 29540913 2018
CUI: C0004936
Disease: Mental disorders
Mental disorders
0.010 GeneticVariation group BEFREE Using the S-PTD, delirium was identified in 72 (25.0%), while an expert neuropsychiatric examination, based on DSM-5 identified delirium in 75 (26.0%) patients. 30314583 2018
CUI: C0005699
Disease: Blast Phase
Blast Phase
0.010 Biomarker disease BEFREE MLL-PTD in a 13-year-old patient with blast phase myeloproliferative neoplasm: A case report. 30431598 2018
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.010 Biomarker disease BEFREE The PTD modified paclitaxel anti-resistant liposomes may provide a promising strategy for treatment of the drug-resistant non-small cell lung cancer. 28480778 2018
CUI: C0008495
Disease: Chorioamnionitis
Chorioamnionitis
0.010 Biomarker phenotype BEFREE Gene expression of 50 ABC transporters was assessed using TaqMan® Human ABC Transporter Array, in preterm human placentas without (PTD; n=6) or with histological chorioamnionitis (PTDC; n=6). 29402780 2018
CUI: C0011206
Disease: Delirium
Delirium
0.010 GeneticVariation disease BEFREE Using the S-PTD, delirium was identified in 72 (25.0%), while an expert neuropsychiatric examination, based on DSM-5 identified delirium in 75 (26.0%) patients. 30314583 2018
CUI: C0019693
Disease: HIV Infections
HIV Infections
0.010 Biomarker group BEFREE Rilpivrine is BCS class II drug used for treatment of HIV infection. 29869305 2018
CUI: C0023290
Disease: Leishmaniasis, Visceral
Leishmaniasis, Visceral
0.010 Biomarker disease BEFREE Buparvaquone (BPQ), a hydroxynapthoquinone with in vitro activity in the nanomolar range, failed to clinically translate as a viable treatment for visceral leishmaniasis due to its poor oral bioavailability limited by its poor aqueous solubility (BCS Class II drug). 29762040 2018
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.010 Biomarker disease BEFREE The mediating effects of seeking social support and engaging in wishful thinking on the PTSD symptoms and PTD link were, however, non-significant. 30319492 2018
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.010 GeneticVariation disease BEFREE To synthesize the prevalence of CALR mutations according to the different types (i.e., Budd-Chiari syndrome [BCS] and portal vein thrombosis [PVT]) and characteristics (i.e., with and without myeloproliferative neoplasms [MPNs] and JAK2V617F mutation) of SVT patients. 29803161 2018
CUI: C0149893
Disease: Secondary glaucoma
Secondary glaucoma
0.010 Biomarker disease BEFREE Finally, because secondary glaucoma is not a feature of BCS1, we speculate that the onlay graft may have reduced aqueous outflow by compression of the thinned sclera. 30115710 2018
CUI: C0155773
Disease: Portal Vein Thrombosis
Portal Vein Thrombosis
0.010 Biomarker disease BEFREE To synthesize the prevalence of CALR mutations according to the different types (i.e., Budd-Chiari syndrome [BCS] and portal vein thrombosis [PVT]) and characteristics (i.e., with and without myeloproliferative neoplasms [MPNs] and JAK2V617F mutation) of SVT patients. 29803161 2018
CUI: C0238033
Disease: Carcinoma of Male Breast
Carcinoma of Male Breast
0.010 Biomarker disease BEFREE Since overall prognosis and systemic therapy recommendations for MBC are similar to breast cancer in women, we describe the first case of MBC treated with BCS and IORT. 28597470 2018
CUI: C0242787
Disease: Malignant neoplasm of male breast
Malignant neoplasm of male breast
0.010 Biomarker disease BEFREE Since overall prognosis and systemic therapy recommendations for MBC are similar to breast cancer in women, we describe the first case of MBC treated with BCS and IORT. 28597470 2018
CUI: C0268344
Disease: Ehlers-Danlos syndrome 6B
Ehlers-Danlos syndrome 6B
0.010 GeneticVariation disease BEFREE Brittle cornea syndrome (BCS1 OMIM #229200, BCS2 #614170) is a rare autosomal recessive condition characterised by diffuse thinning and fragility of the cornea. 30115710 2018
CUI: C0339682
Disease: Regular astigmatism - corneal
Regular astigmatism - corneal
0.010 Biomarker disease BEFREE We describe a 9-year-old girl with BCS1, already blind in one eye following trauma, who had a 14 mm diameter corneoscleral onlay graft to her contralateral eye to reduce gross irregular corneal astigmatism and potentially to reduce further risk from accidental injury. 30115710 2018
CUI: C0729665
Disease: Arteriovenous graft
Arteriovenous graft
0.010 Biomarker disease BEFREE We report a case of vein rupture by Arrow-Trerotola percutaneous thrombolytic device (Trerotola PTD) during a treatment of thrombosed arteriovenous graft (AVG). 29529963 2018
CUI: C0853879
Disease: Invasive carcinoma of breast
Invasive carcinoma of breast
0.010 Biomarker disease BEFREE Women under age 70 with invasive breast cancer who underwent BCS from 2004 to 2014 were analyzed. 30083949 2018
CUI: C1292778
Disease: Chronic myeloproliferative disorder
Chronic myeloproliferative disorder
0.010 Biomarker disease BEFREE MLL-PTD in a 13-year-old patient with blast phase myeloproliferative neoplasm: A case report. 30431598 2018
CUI: C2986665
Disease: Early-Stage Breast Carcinoma
Early-Stage Breast Carcinoma
0.010 Biomarker disease BEFREE After discussion among our multidisciplinary tumor board, we felt this patient to be suitable for BCS and IORT given his age, favorable tumor subtype, size, and clinically early stage breast cancer. 28597470 2018