|
Arthritis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Emerging evidence from this study signposts CIA in the DBA/1 mouse as a model that is relevant to study the development and treatment of early cardiovascular pathology associated with inflammatory arthritis.
|
28425846 |
2017 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Exposure of DBA/1 mice to the mold metabolites ochratoxin A (OTA) or deoxynivalenol (DON) increased the prevalence and the clinical severity of RA compared to un-exposed mice using an experimental collagen-induced arthritis model.
|
28935500 |
2017 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
In DBA/1 mouse collagen-induced arthritis model, recombinant human IL-20R2-Fc exhibits comparable efficacy as TNF blocker etanercept in the treatment of established arthritis, whereas the combined use of both biologics manifests little synergistic therapeutic effects.
|
27619991 |
2016 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
DBA/1 mice doubly deficient in IL-4 and IL-10 were used to confirm that these two cytokines are important for the APL-induced attenuation of arthritis.
|
27837109 |
2016 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
In this study, we performed 16S rRNA sequencing to characterise the gut microbiota of DBA1 mice that did or did not develop arthritis after induction with collagen.
|
27481047 |
2016 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Mice overexpressing IGF-I in the osteoblast lineage (Ob-IGF-I+/-) line 324-7 were studied during collagen induced arthritis and in the DBA/1 aging model for ankylosing enthesitis.
|
27695067 |
2016 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
L. salivarius UCC118 or L. plantarum WCFS1 isolated from patients with RA was administered orally for 5 weeks, starting from 2 weeks before the induction of arthritis in DBA/1 mice.
|
27845855 |
2016 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Similar to the NZB/W model, pristane-induced disease in SJL mice manifests with nephritis and proteinuria, whereas the pristane-treated DBA/1 mice develop arthritis and an interferon-driven gene signature that closely resembles that in human patients.
|
24462761 |
2014 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Immunization with human glucose-6-phosphate isomerase (hG6PI) protein or with several of its peptides induces arthritis in DBA/1 mice.
|
23911657 |
2013 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Ovariectomy was followed by collagen-induced arthritis in female DBA-1/J mice.
|
22644323 |
2012 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
DBA/1J mice with CIA that received IL-17-/- donor bone marrow showed potently inhibited development and severity of clinical arthritis as compared with CIA mice that received WT bone marrow.
|
23114425 |
2012 |
|
Arthritis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
CIA was induced in DBA/1J mice.Arthritic mice were treated with bosentan (100 mg/kg) once a day, starting from the day when arthritis was clinically detectable.
|
22249931 |
2012 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Following immunization with collagen II (CII) in complete Freund's adjuvant (CFA), DBA/1 mice develop arthritis of major joints.
|
22930199 |
2012 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
In contrast to the situation in humans, lpxL1 LPS has agonistic activity for cytokine production in peritoneal macrophages of DBA mice, and exacerbated arthritis in murine collagen induced arthritis model.
|
21088052 |
2011 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
DBA/1 mice were immunized with bovine type II collagen (bCII) to induce arthritis.
|
21345239 |
2011 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
In the induced arthritis models PIA and CIA, the transgenic mice developed a more severe arthritis than the other arthritis-prone SJL or DBA1 mice.
|
20005897 |
2010 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
DBA/1 mice were immunized with type II collagen to induce arthritis.
|
19866480 |
2010 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
MHC class II derived recombinant T cell receptor ligands protect DBA/1LacJ mice from collagen-induced arthritis.
|
18178865 |
2008 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Furthermore, the in vivo depletion of CD4(+)CD25(+) T(regs) in (DBA/1 x C57BL/6)F(1) Tg2 mice promotes the development of a severe collagen type II-induced arthritis.
|
17312121 |
2007 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Furthermore, injection of anti-CD44vRA mAbs reduced joint inflammation in DBA/1 mice with collagen-induced arthritis.
|
17383158 |
2007 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
In D1CC mice congenic for the H-2(q) (DBA/1) background, small amounts of bovine collagen type II in adjuvant induced reproducibly an inflammatory arthritis resembling RA.
|
16980409 |
2006 |
|
Arthritis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Immunization of PECAM-1(-/-) C57BL/6 (H-2b) mice with chicken collagen type II induced CIA with an incidence of 82% by day 49, while 33%; of wild-type and 100% of DBA/1 mice developed arthritis in a similar time frame.
|
15742154 |
2005 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Here we report that this process partially recapitulates embryonic endochondral bone formation in a spontaneous model of arthritis in DBA/1 mice.
|
15902307 |
2005 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Two autoimmune murine models--proteoglycan (aggrecan)-induced arthritis (PGIA) and collagen-induced arthritis (CIA)--were developed in parent strains, F1 and F2 hybrids of major histocompatibility complex (MHC)-matched (H-2) BALB/c x DBA/2 and MHC-unmatched (H-2/H-2) BALB/c x DBA/1 intercrosses.
|
15084914 |
2004 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
When DBA/1 mice were immunized with rCII, rCII(pic) induced a lower incidence of arthritis than tissue-derived CII, whereas rCII(bac) induced an intermediate level of arthritis.
|
14978100 |
2004 |