BDKRB1, bradykinin receptor B1, 623

N. diseases: 79; N. variants: 2
Disease: Hypertensive disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.230 Biomarker group BEFREE The Effects of Bradykinin B1 Receptor Antagonism on the Myocardial and Vascular Consequences of Hypertension in SHR Rats. 31178756 2019
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.230 Biomarker group BEFREE Our data provide the first evidence of a central role for B1R-mediated inflammatory pathways in the pathogenesis of deoxycorticosterone acetate-salt hypertension and offer novel insights into possible B1R-targeted therapies for the treatment of neurogenic hypertension. 29038201 2017
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.230 Biomarker group RGD Involvement of kinin B1 receptor and oxidative stress in sensory abnormalities and arterial hypertension in an experimental rat model of insulin resistance. 17988733 2007
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.230 GeneticVariation group BEFREE One SNP in BDKRB2 and three SNPs in BDKRB1 were associated with hypertension (P-values between 0.026 and 0.0004) in American-Caucasians. 15643125 2005
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.230 Biomarker group RGD Kinin B1 and B2 receptor mRNA expression in the hypothalamus of spontaneously hypertensive rats. 12025958 2002