BDKRB1, bradykinin receptor B1, 623

N. diseases: 79; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental 		0.500 Biomarker disease CTD_human Enalaprilat-mediated activation of kinin b(1) receptors and vasodilation in the rat isolated perfused kidney. 21430409 2011
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia 		0.500 Biomarker phenotype CTD_human Bradykinin receptor antagonists and cyclooxygenase inhibitors in vincristine- and streptozotocin-induced hyperalgesia. 19815945 2010
CUI: C0030193
Disease: Pain
Pain 		0.500 Biomarker phenotype CTD_human Kinin B1 receptors contributes to acute pain following minor surgery in humans. 20152050 2010
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia 		0.500 Biomarker phenotype CTD_human Bradykinin receptors antagonists and nitric oxide synthase inhibitors in vincristine and streptozotocin induced hyperalgesia in chemotherapy and diabetic neuropathy rat model. 19300402 2009
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental 		0.500 Biomarker disease RGD Retinal plasma extravasation in streptozotocin-diabetic rats mediated by kinin B(1) and B(2) receptors. 18311190 2008
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia 		0.500 Biomarker phenotype CTD_human Effect of bradykinin receptor antagonists on vincristine- and streptozotocin-induced hyperalgesia in a rat model of chemotherapy-induced and diabetic neuropathy. 17989505 2008
CUI: C0030193
Disease: Pain
Pain 		0.500 Biomarker phenotype RGD Involvement of kinin B1 receptor and oxidative stress in sensory abnormalities and arterial hypertension in an experimental rat model of insulin resistance. 17988733 2007
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental 		0.500 Biomarker disease RGD Up-regulation of kinin B1 receptor in the lung of streptozotocin-diabetic rat: autoradiographic and functional evidence. 12522068 2003
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia 		0.500 Biomarker phenotype RGD Therefore we have examined B1 bradykinin receptor regulation in rat dorsal root ganglia in a model of inflammatory hyperalgesia, and correlated it with hyperalgesic behaviour. 12927641 2003
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental 		0.500 Biomarker disease RGD Regulation of cardiac bradykinin B1- and B2-receptor mRNA in experimental ischemic, diabetic, and pressure-overload-induced cardiomyopathy. 12489796 2002
CUI: C0021368
Disease: Inflammation
Inflammation 		0.310 Biomarker phenotype CTD_human Kinin B1 receptors contributes to acute pain following minor surgery in humans. 20152050 2010
CUI: C0021368
Disease: Inflammation
Inflammation 		0.310 Biomarker phenotype LHGDN Increased B(1)R gene and protein expression in active IBD provides a structural basis of the important role of bradykinin in chronic inflammation. 15805101 2005
CUI: C0002152
Disease: Alloxan Diabetes
Alloxan Diabetes 		0.300 Biomarker disease CTD_human Enalaprilat-mediated activation of kinin b(1) receptors and vasodilation in the rat isolated perfused kidney. 21430409 2011
CUI: C0038433
Disease: Streptozotocin Diabetes
Streptozotocin Diabetes 		0.300 Biomarker disease CTD_human Enalaprilat-mediated activation of kinin b(1) receptors and vasodilation in the rat isolated perfused kidney. 21430409 2011
CUI: C0038002
Disease: Splenomegaly
Splenomegaly 		0.300 Biomarker phenotype CTD_human Myelopoiesis modulation by ACE hyperfunction in kinin B(1) receptor knockout mice: relationship with AcSDKP levels. 20096676 2010
CUI: C0234230
Disease: Pain, Burning
Pain, Burning 		0.300 Biomarker phenotype CTD_human Kinin B1 receptors contributes to acute pain following minor surgery in humans. 20152050 2010
CUI: C0234238
Disease: Ache
Ache 		0.300 Biomarker phenotype CTD_human Kinin B1 receptors contributes to acute pain following minor surgery in humans. 20152050 2010
CUI: C0234254
Disease: Radiating pain
Radiating pain 		0.300 Biomarker phenotype CTD_human Kinin B1 receptors contributes to acute pain following minor surgery in humans. 20152050 2010
CUI: C0458247
Disease: Allodynia
Allodynia 		0.300 Biomarker phenotype CTD_human Bradykinin receptor antagonists and cyclooxygenase inhibitors in vincristine- and streptozotocin-induced hyperalgesia. 19815945 2010
CUI: C0458257
Disease: Pain, Splitting
Pain, Splitting 		0.300 Biomarker phenotype CTD_human Kinin B1 receptors contributes to acute pain following minor surgery in humans. 20152050 2010
CUI: C0458259
Disease: Pain, Crushing
Pain, Crushing 		0.300 Biomarker phenotype CTD_human Kinin B1 receptors contributes to acute pain following minor surgery in humans. 20152050 2010
CUI: C0751211
Disease: Hyperalgesia, Primary
Hyperalgesia, Primary 		0.300 Biomarker phenotype CTD_human Bradykinin receptor antagonists and cyclooxygenase inhibitors in vincristine- and streptozotocin-induced hyperalgesia. 19815945 2010
CUI: C0751212
Disease: Hyperalgesia, Secondary
Hyperalgesia, Secondary 		0.300 Biomarker phenotype CTD_human Bradykinin receptor antagonists and cyclooxygenase inhibitors in vincristine- and streptozotocin-induced hyperalgesia. 19815945 2010
CUI: C0751213
Disease: Tactile Allodynia
Tactile Allodynia 		0.300 Biomarker phenotype CTD_human Bradykinin receptor antagonists and cyclooxygenase inhibitors in vincristine- and streptozotocin-induced hyperalgesia. 19815945 2010
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.300 Biomarker phenotype CTD_human Bradykinin receptor antagonists and cyclooxygenase inhibitors in vincristine- and streptozotocin-induced hyperalgesia. 19815945 2010