BDNF, brain derived neurotrophic factor, 627

N. diseases: 992; N. variants: 56
Disease: Nerve Degeneration ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027746
Disease: Nerve Degeneration
Nerve Degeneration 		0.500 Biomarker phenotype CTD_human Exogenous BDNF prevented dopaminergic neurodegeneration, and the neuroprotective effect of Am80 was suppressed by a TrkB inhibitor, K252a, or by anti-BDNF neutralizing antibody. 19457078 2009
CUI: C0027746
Disease: Nerve Degeneration
Nerve Degeneration 		0.500 Biomarker phenotype CTD_human Brain-derived neurotrophic factor facilitates TrkB down-regulation and neuronal injury after status epilepticus in the rat hippocampus. 19686240 2009
CUI: C0027746
Disease: Nerve Degeneration
Nerve Degeneration 		0.500 Therapeutic phenotype CTD_human Exogenous BDNF prevented dopaminergic neurodegeneration, and the neuroprotective effect of Am80 was suppressed by a TrkB inhibitor, K252a, or by anti-BDNF neutralizing antibody. 19457078 2009
CUI: C0027746
Disease: Nerve Degeneration
Nerve Degeneration 		0.500 Therapeutic phenotype CTD_human Brain-derived neurotrophic factor facilitates TrkB down-regulation and neuronal injury after status epilepticus in the rat hippocampus. 19686240 2009
CUI: C0027746
Disease: Nerve Degeneration
Nerve Degeneration 		0.500 Biomarker phenotype RGD Cortical expression of brain derived neurotrophic factor and type-1 cannabinoid receptor after striatal excitotoxic lesions. 18313855 2008
CUI: C0027746
Disease: Nerve Degeneration
Nerve Degeneration 		0.500 Biomarker phenotype CTD_human Delayed neurotrophic treatment preserves nerve survival and electrophysiological responsiveness in neomycin-deafened guinea pigs. 15372491 2004
CUI: C0027746
Disease: Nerve Degeneration
Nerve Degeneration 		0.500 Therapeutic phenotype CTD_human Delayed neurotrophic treatment preserves nerve survival and electrophysiological responsiveness in neomycin-deafened guinea pigs. 15372491 2004
CUI: C0027746
Disease: Nerve Degeneration
Nerve Degeneration 		0.500 Biomarker phenotype CTD_human Neurotrophin protection against toxicity induced by low potassium and nitroprusside in cultured cerebellar granule neurons. 8978711 1997
CUI: C0027746
Disease: Nerve Degeneration
Nerve Degeneration 		0.500 Therapeutic phenotype CTD_human Neurotrophin protection against toxicity induced by low potassium and nitroprusside in cultured cerebellar granule neurons. 8978711 1997
CUI: C0027746
Disease: Nerve Degeneration
Nerve Degeneration 		0.500 Biomarker phenotype CTD_human Differential damage to auditory neurons and hair cells by ototoxins and neuroprotection by specific neurotrophins in rat cochlear organotypic cultures. 8921280 1996
CUI: C0027746
Disease: Nerve Degeneration
Nerve Degeneration 		0.500 Therapeutic phenotype CTD_human Differential damage to auditory neurons and hair cells by ototoxins and neuroprotection by specific neurotrophins in rat cochlear organotypic cultures. 8921280 1996