Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.340 AlteredExpression disease BEFREE Recent evidence suggests a putative role for S100B as a state marker of illness activity as it is found elevated in episodes of major depression. 31493698 2019
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.340 AlteredExpression disease BEFREE S100B levels in serum were consistently elevated in studies with statistically significant results which investigated acute affective episodes (comprising major depressive episode in major depressive disorder, and both manic and depressive episodes in patients with bipolar disorder), in comparison to healthy controls. 29764272 2018
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.340 Biomarker disease PSYGENET These genes include GRM7, previously associated to major depression disorder and bipolar disorder, SLC6A13, in anxiety disorders, and S100B, SSTR5 and COMT in schizophrenia. 20398908 2010
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.340 Biomarker disease PSYGENET The etiology of major depression remains unknown, but dysfunction of serotonergic signaling has long been implicated in the pathophysiology of this disorder. p11 is an S100 family member recently identified as a serotonin 1B [5-hydroxytryptamine 1B (5-HT(1B))] and serotonin 4 (5-HT(4)) receptor-binding protein. 20962330 2010
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.340 GeneticVariation disease BEFREE Our findings did not suggest association of S100B gene polymorphisms in patients with MDD in China. 19497163 2009
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.340 Biomarker disease PSYGENET Our findings did not suggest association of S100B gene polymorphisms in patients with MDD in China. 19497163 2009
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.340 GeneticVariation disease BEFREE S100B rs9722 C > T polymorphism appears not to be an important factor in susceptibility to MDD in a Chinese population. 18939940 2008
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.340 Biomarker disease PSYGENET S100B rs9722 C > T polymorphism appears not to be an important factor in susceptibility to MDD in a Chinese population. 18939940 2008