|
Acute GVH disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Grade 2-4 acute graft-versus-host disease (GVHD) at 100-day post-DLI was higher in HID-SCT group than that in MSD-SCT group (59.5% vs. 30.8%, p = 0.05).
|
30747249 |
2019 |
|
Acute GVH disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
The risk of acute graft-versus-host disease (GVHD) is significantly higher after HID-SCT versus ISD-SCT (OR = 1.88, 95% CI = 1.42-2.49, P < 0.00001), but the relapse rate is lower in HID-SCT group (OR = 0.70, 95% CI = 0.55-0.90, P = 0.005).
|
29381772 |
2018 |
|
Acute GVH disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Univariate analysis showed that MRD-WT1 negativity pre-SCT and grade <2 acute GVHD were significant prognostic factors for improved OS and DFS.
|
29096332 |
2017 |
|
Acute GVH disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
All patients underwent 10/10 HLA-matched peripheral blood allo-SCT (sibling donor for first and third patients and unrelated donor for the second patient; all had acute graft-versus-host disease (GVHD), and the first and third patients had chronic GVHD.
|
24994916 |
2014 |
|
Acute GVH disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Fanconi anemia (FA) patients have an increased risk of acute GVHD (aGVHD) after hematopoietic SCT, with hypersensitivity to DNA-cross-linking agents and defective DNA repair.
|
23222379 |
2013 |
|
Acute GVH disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
We performed a retrospective analysis of HLA-G 14 bp polymorphism using a specific PCR in 47 recipients and in their respective donors, and evaluated the correlation with the incidence of aGvHD, OS and disease-free survival (DFS) after allo-SCT.
|
21399669 |
2012 |
|
Acute GVH disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
The impact of KIR2DS4 alleles and the expression of KIR in the development of acute GVHD after unrelated allogeneic hematopoietic SCT.
|
20062104 |
2010 |
|
Acute GVH disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Recent insight into the pathophysiology of acute GVHD after allogeneic haematopoietic SCT has led to a growing interest in the role of natural killer (NK) cells.
|
20173792 |
2010 |
|
Acute GVH disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Single nucleotide polymorphisms (SNPs) in genes of the immune system predict for aGVHD and mortality after allo-SCT.
|
20541026 |
2010 |
|
Acute GVH disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Despite advances in prevention and post transplant immuno-suppressive strategies, acute GvHD (aGvHD) remains a major cause of morbidity and mortality in children undergoing SCT.
|
18545246 |
2008 |
|
Acute GVH disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
In multivariate analysis, when adjusted for the European Group for Blood and Marrow Transplantation (EBMT)-Gratwohl score and other prog-nostic factors, there was an independent association between BMI-1 expression and grades 2 to 4 acute graft-versus-host disease (relative risk [RR] = 2.85; 95% confidence interval [CI], 1.3-6.4; P = .011), suggesting that BMI-1 measured prior to allo-SCT can serve as a biomarker for predicting outcome in patients with CP-CML receiving allo-SCT, and may thus contribute to better therapeutic decisions.
|
18565849 |
2008 |
|
Acute GVH disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Four patients died after allo-SCT during the study period from either acute GVHD (grade IV), pneumonitis, gastrointestinal bleeding or renal insufficiency.
|
11244433 |
2001 |