|
Glomerulonephritis
|
0.390 |
Biomarker
|
disease |
BEFREE |
To determine the performance of urine EGF, MCP-1 or their ratio at baseline as biomarkers to predict complete remission, and the relationship of these mediators with subsequent renal function 24 months later in primary glomerulonephritis.
|
29414320 |
2018 |
|
Glomerulonephritis
|
0.390 |
AlteredExpression
|
disease |
BEFREE |
The protective role of Foxp3 in crescentic GN was associated with a markedly suppressed expression of proinflammatory interleukin-1 beta (IL-1β), tumour necrosis factor-alpha (TNF-α) and monocyte chemoattractant protein 1 (MCP-1), and diminished infiltration of the kidneys by CD3<sup>+</sup> T cells and F4/80<sup>+</sup> macrophages.
|
28469165 |
2017 |
|
Glomerulonephritis
|
0.390 |
AlteredExpression
|
disease |
BEFREE |
Our data indicate that Fli-1 impacts glomerulonephritis development by regulating expression of inflammatory chemokine MCP-1 and inflammatory cell infiltration in the kidneys in the NZM2410 mice.
|
23108091 |
2012 |
|
Glomerulonephritis
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
Odds Ratio (OR) for GN patients with the MCP-1 -2518 GG genotype was 0.869 (95% CI = 0.410-1.840, P = 0.7130), and OR of the -2518 GG and -2518AG genotypes was 1.004 (95% CI = 0.689-1.464, P = 0.9836).
|
22203484 |
2012 |
|
Glomerulonephritis
|
0.390 |
AlteredExpression
|
disease |
BEFREE |
In contrast TLR3 mRNA expression was significantly increased in hepatitis C-positive glomerulonephritis and was associated with enhanced mRNA for RANTES/CCL5 and MCP-1/CCL2.
|
16436653 |
2006 |
|
Glomerulonephritis
|
0.390 |
Biomarker
|
disease |
CTD_human |
We previously reported that the gene expression of six CC chemokines-MCP-1, MCP-3, MIP-1alpha, MIP-1beta, RANTES, and TCA3-was enhanced in a rat model of crescentic glomerulonephritis, the most severe form of glomerulonephritis.
|
10385480 |
1999 |
|
Glomerulonephritis
|
0.390 |
Biomarker
|
disease |
BEFREE |
Using in situ hybridization (ISH) we analyzed the expression of mRNA for the C-C chemokines monocyte chemoattractant protein-1 (MCP-1), macrophage inflammatory protein-1alpha and beta (MIP-1alpha, MIP-1beta) and RANTES in renal biopsy material from twenty patients with glomerulonephritis.
|
9734607 |
1998 |
|
Glomerulonephritis
|
0.390 |
Biomarker
|
disease |
BEFREE |
These results demonstrate the cytokine-induced production of MCP-1 by GEN at gene and protein levels as well as bioactivity, and suggest that GEN may participate in the development of glomerulonephritis through the production of MCP-1.
|
8587246 |
1995 |
|
Glomerulonephritis
|
0.390 |
Biomarker
|
disease |
BEFREE |
Recent findings that monocyte chemoattractant protein-1 (MCP-1), a chemotactic cytokine with a high degree of specificity for lymphocytes and monocytes, is overexpressed in glomeruli from rats with immunecomplex glomerulonephritis prompted us to explore the possibility that MCP-1 could be implicated in the renal inflammatory response of lupus erythematosus.
|
8558841 |
1995 |
|
Glomerulonephritis
|
0.390 |
AlteredExpression
|
disease |
BEFREE |
MCP-1 mRNA was transiently upregulated during the early stages of experimental GN.
|
7967509 |
1994 |