CCL2, C-C motif chemokine ligand 2, 6347

N. diseases: 1157; N. variants: 8
Disease: Endometrial Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.350 Biomarker disease BEFREE Taken together, our findings suggest that ATF4 contributes to tumor growth of EC by promoting CCL2 and subsequent recruitment of macrophage, and that ATF4/CCL2 axis might be a potential therapeutic target for EC. 28843961 2017
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.350 AlteredExpression disease BEFREE Unfractionated Heparin Selectively Modulates the Expression of CXCL8, CCL2 and CCL5 in Endometrial Carcinoma Cells. 27069129 2016
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.350 Biomarker disease BEFREE These data demonstrate that CCL2 is a potent effector of LKB1 loss in endometrial cancer, creating potential avenues for therapeutic opportunities. 26413869 2015
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.350 GeneticVariation disease BEFREE In conclusion, we state that there appears to be an association between polymorphism of CCL2 and its receptor CCR2 and endometrial cancer. 20364004 2010
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.350 AlteredExpression disease BEFREE Tamoxifen inhibited MCP-1 mRNA and protein expression in endometrial cancer cells and inhibited MCP-1 secretion in a time- and dose-dependent manner at concentrations of 10(-7) to 10(-5) M. Buserelin had no significant effect on MCP-1 mRNA and protein expression. 16866022 2007
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.350 Biomarker disease CTD_human The effect of COX-2 inhibitor, nimesulide, on angiogenetic factors in primary endometrial carcinoma cell culture. 17380299 2007