CCL2, C-C motif chemokine ligand 2, 6347

N. diseases: 1157; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
0.040 AlteredExpression disease BEFREE Furthermore, TIPE1 inhibits the infiltration of macrophages in osteosarcoma tumor by suppressing MCP-1 expression in osteosarcoma cells. 30062520 2019
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
0.040 AlteredExpression disease BEFREE These results suggested that the expression of CCL2 is high in high-grade osteosarcoma cells and promotes the proliferation and invasion of osteosarcoma cells. 25695619 2015
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
0.040 Biomarker disease BEFREE We have previously reported that titanium particles stimulate the selective induction of interleukin-8 (IL-8) and monocyte chemoattractant protein-1 (MCP-1) chemokines in human osteoblast-like osteosarcoma cells. 16392133 2006
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
0.040 AlteredExpression disease BEFREE We now report that the MCP-1 gene is expressed in MG-63 human osteosarcoma and vascular smooth muscle cells and that SMC-CF antiserum specifically immunoprecipitates proteins synthesized by U-105MG glioma cells. 2211704 1990