Middle Cerebral Artery Occlusion
|
0.360 |
AlteredExpression
|
disease |
BEFREE |
Ex-4 improved neurologic deficit scores, reduced the infarct area, and ameliorated BBB breakdown as well as decreased astrocyte-derived VEGF-A, MMP-9, CXCL-1, and MCP-1 levels in ischemic brain tissues from rats subjected to middle cerebral artery occlusion.
|
31779652 |
2019 |
Middle Cerebral Artery Occlusion
|
0.360 |
Biomarker
|
disease |
BEFREE |
<b>Methods:</b> Using the middle cerebral artery occlusion (MCAO) model of ischemic stroke, we identified that CCL2 is one of the most highly expressed chemokines in the ipsilateral hemisphere.
|
30613272 |
2018 |
Middle Cerebral Artery Occlusion
|
0.360 |
AlteredExpression
|
disease |
BEFREE |
Downregulating the PDGFR signaling pathway with crenolanib from day 1 to day 3 after MCAO significantly decreased the migration of neuroblasts from the SVZ to the peri-infarct region, decreased angiogenesis, and lowered expression of vascular endothelial growth factor, stromal cell-derived factor-1, and monocyte chemotactic protein-1.
|
28943249 |
2017 |
Middle Cerebral Artery Occlusion
|
0.360 |
Biomarker
|
disease |
CTD_human |
PACAP38 differentially effects genes and CRMP2 protein expression in ischemic core and penumbra regions of permanent middle cerebral artery occlusion model mice brain.
|
25257527 |
2014 |
Middle Cerebral Artery Occlusion
|
0.360 |
Therapeutic
|
disease |
CTD_human |
PACAP38 differentially effects genes and CRMP2 protein expression in ischemic core and penumbra regions of permanent middle cerebral artery occlusion model mice brain.
|
25257527 |
2014 |
Middle Cerebral Artery Occlusion
|
0.360 |
Biomarker
|
disease |
CTD_human |
Hypoxic preconditioning induces stroke tolerance in mice via a cascading HIF, sphingosine kinase, and CCL2 signaling pathway.
|
23043544 |
2012 |
Middle Cerebral Artery Occlusion
|
0.360 |
Therapeutic
|
disease |
CTD_human |
Hypoxic preconditioning induces stroke tolerance in mice via a cascading HIF, sphingosine kinase, and CCL2 signaling pathway.
|
23043544 |
2012 |
Middle Cerebral Artery Occlusion
|
0.360 |
AlteredExpression
|
disease |
BEFREE |
Here, we report that middle cerebral artery occlusion increases the expression of MCP-1 and the recruitment of neutrophils into the ischemic tissue in Wt but not in TWEAK(-/-) or Fn14(-/-) mice.
|
20068578 |
2010 |
Middle Cerebral Artery Occlusion
|
0.360 |
Biomarker
|
disease |
CTD_human |
A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke.
|
12374626 |
2002 |
Middle Cerebral Artery Occlusion
|
0.360 |
Therapeutic
|
disease |
CTD_human |
A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke.
|
12374626 |
2002 |
Middle Cerebral Artery Occlusion
|
0.360 |
AlteredExpression
|
disease |
BEFREE |
-MCP-1 and MIP-1alpha expression is increased after middle cerebral artery occlusion, and double-labeled immunostaining revealed that MCP-1 is colocalized with neurons and astrocytes.
|
11157195 |
2001 |
Middle Cerebral Artery Occlusion
|
0.360 |
Biomarker
|
disease |
BEFREE |
Using the Middle Cerebral Artery Occlusion (MCAO) mouse model, this study demonstrated that, in vivo, both endothelin-1 (Et-1), a potent vasoconstrictor, and the macrophage chemokine, monocyte chemoattractant factor-1 (MCP-1) are induced in ischemia.
|
11311331 |
2001 |