CCL2, C-C motif chemokine ligand 2, 6347

N. diseases: 1157; N. variants: 8
Disease: Neointimal hyperplasia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4049446
Disease: Neointimal hyperplasia
Neointimal hyperplasia 		0.040 Biomarker disease BEFREE The suppressive effect of monocyte chemoattractant protein-1 suggests that it plays a key role in neointimal hyperplasia. 30609436 2019
CUI: C4049446
Disease: Neointimal hyperplasia
Neointimal hyperplasia 		0.040 Biomarker disease BEFREE Deletion of monocyte chemoattractant protein-1 in PVAT substantially attenuated the effects of fat transplantation on neointimal hyperplasia and adventitial angiogenesis, but not adventitial macrophage infiltration. 24947528 2014
CUI: C4049446
Disease: Neointimal hyperplasia
Neointimal hyperplasia 		0.040 AlteredExpression disease BEFREE In conclusion, cilostazol administered with LPS in vivo reduced neointimal hyperplasia and macrophage infiltration in the balloon-injured rabbit aorta; in vitro, cilostazol inhibits LPS-induced MCP-1 and MMP-9 expression. 17516547 2008
CUI: C4049446
Disease: Neointimal hyperplasia
Neointimal hyperplasia 		0.040 Biomarker disease BEFREE The MCP-1/CCR2 pathway plays a central role in the pathogenesis of neointimal hyperplasia in cuffed femoral artery of mice and monkeys. 12065319 2002