|
Primary malignant neoplasm of lung
|
0.030 |
Biomarker
|
disease |
BEFREE |
Therefore, the findings indicated that CX3CL1 promotes lung cancer cell migration and invasion in vitro, and the Src/FAK signaling pathway serves a vital role in this process.
|
30628679 |
2019 |
|
Celiac Disease
|
0.020 |
Biomarker
|
disease |
BEFREE |
CX3CL1 seems to be involved in the appearance and progression of CD, and it appears to be a potential diagnostic biomarker.
|
31652730 |
2019 |
|
Multiple Myeloma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Our data indicate that CX3CL1, present at a high level in the BM of MM patients, is a new player of the MM microenvironment involved in MM-induced angiogenesis.
|
30845779 |
2019 |
|
Pulmonary Emphysema
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
Through multivariate logistic regression analysis, it was found that high serum CX3CL1 levels were independently associated with emphysema, with a relative risk of 2.617 (95% CI 1.018-6.121; P = 0.029).
|
30382361 |
2019 |
|
Acute myocardial infarction
|
0.020 |
Biomarker
|
disease |
BEFREE |
Prognostic value of fractalkine/CX3CL1 concentration in patients with acute myocardial infarction treated with primary percutaneous coronary intervention.
|
30352758 |
2019 |
|
Stable angina
|
0.020 |
Biomarker
|
disease |
BEFREE |
Transcoronary (TC) levels of chemokine ligand 2 (CCL2) and C-X3-C motif chemokine ligand 1 (CX3CL1) were significantly elevated in patients with ACS versus patients with SAP (P < 0.01).
|
31409556 |
2019 |
|
Middle Cerebral Artery Occlusion
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
In the present study, to investigate whether autophagy could alter CX3CL1 expression on neurons and consequently change microglial inflammatory activity, middle cerebral artery occlusion (MCAO) was established in Sprague-Dawley rats to model ischemic stroke, and tissues from the ischemic penumbra were obtained to evaluate autophagy level and microglial inflammatory activity.
|
30531011 |
2019 |
|
Acute Chest Syndrome
|
0.020 |
Biomarker
|
disease |
BEFREE |
Transcoronary (TC) levels of chemokine ligand 2 (CCL2) and C-X3-C motif chemokine ligand 1 (CX3CL1) were significantly elevated in patients with ACS versus patients with SAP (P < 0.01).
|
31409556 |
2019 |
|
Carcinoma, Ovarian Epithelial
|
0.020 |
Biomarker
|
disease |
BEFREE |
The elevated levels of CX3CR1, which were sensitive to CX3CL1, increased EMT markers that led to the progression and metastasis of OvCa.
|
31077234 |
2019 |
|
Blepharitis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
CX3CL1 levels have significantly increased in SM-exposed group with blepharitis, pterygium, and conjunctival pigmentation as compared with the control group.
|
31669888 |
2019 |
|
Glioma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In addition, the high levels of expression of CX3CL1 were positively correlated with glioma patient survival in the TCGA and CGGA databases, and in the clinical samples.
|
30575118 |
2019 |
|
Monoclonal Gammopathy of Undetermined Significance
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
We found that BM CX3CL1 levels were significantly increased in MM patients compared to SMM and MGUS and correlated with BM microvessel density.
|
30845779 |
2019 |
|
Osteoporosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Recently conducted studies revealed the participation of CX3CL1 chemokine in the pathogenesis of osteoporosis.
|
31780870 |
2019 |
|
Retinitis Pigmentosa
|
0.010 |
Biomarker
|
disease |
BEFREE |
Soluble CX3CL1 gene therapy improves cone survival and function in mouse models of retinitis pigmentosa.
|
31036641 |
2019 |
|
Chronic pain
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
We analyzed the CCL2 gene rs4586, CALCA rs3781719, CX3CL1 rs614230 single nucleotide polymorphism (SNPs) of 350 Chinese Han women with chronic postsurgical pain (CPSP) 6 months after cesarean section and 350 healthy women without chronic pain (HC).
|
31441843 |
2019 |
|
Conjunctival pigmentation
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
CX3CL1 levels have significantly increased in SM-exposed group with blepharitis, pterygium, and conjunctival pigmentation as compared with the control group.
|
31669888 |
2019 |
|
Inflammatory pain
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Inhibition of chemokine CX3CL1 in spinal cord mediates the electroacupuncture-induced suppression of inflammatory pain.
|
31564958 |
2019 |
|
Peritoneal Fibrosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Detection of its ligand CX3CL1 on the peritoneal mesothelium led us to hypothesize a pathophysiologic role of CX3CL1-CX3CR1 interaction in peritoneal fibrosis.
|
30948201 |
2019 |
|
ovarian neoplasm
|
0.010 |
Biomarker
|
disease |
BEFREE |
The elevated levels of CX3CR1, which were sensitive to CX3CL1, increased EMT markers that led to the progression and metastasis of OvCa.
|
31077234 |
2019 |
|
Ischemic stroke
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In the present study, to investigate whether autophagy could alter CX3CL1 expression on neurons and consequently change microglial inflammatory activity, middle cerebral artery occlusion (MCAO) was established in Sprague-Dawley rats to model ischemic stroke, and tissues from the ischemic penumbra were obtained to evaluate autophagy level and microglial inflammatory activity.
|
30531011 |
2019 |
|
Malignant neoplasm of ovary
|
0.010 |
Biomarker
|
disease |
BEFREE |
The elevated levels of CX3CR1, which were sensitive to CX3CL1, increased EMT markers that led to the progression and metastasis of OvCa.
|
31077234 |
2019 |
|
Major Depressive Disorder
|
0.010 |
Biomarker
|
disease |
BEFREE |
The aim of the study was to explore TNF-α, IL-1β, CXCL12, CCL2, CCL11 (eotaxin-1) and CX3CL1 (fractalkine) as potential biomarkers to identify comorbid MDD and to distinguish primary MDD from substance-induced MDD in patients with substance disorders.
|
30870525 |
2019 |
|
Smoldering myeloma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
We found that BM CX3CL1 levels were significantly increased in MM patients compared to SMM and MGUS and correlated with BM microvessel density.
|
30845779 |
2019 |
|
Liver carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Theses reviewed in this issue include "Alpha-Synuclein Oligomers: Cellular Mechanisms and Aspects of Antibody Treatment," "Cx3cr1/cx3cl1 Axis Drives the Migration and Maturation of Oligodendroglia in the Central Nervous System," "Genome-Wide Expression Profiling of Human Circulating Monocytes and Macrophages Identifies Diagnostic and Prognostic Signatures for Cancer Outcomes," "Lysosomal Oxidation of Low Density Lipoproteins," and "The Senescence-Associated Secretory Phenotype Induced by ID1-p16 Axis Contributes to Sorafenib Resistance in Hepatocellular Carcinoma."
|
30957657 |
2019 |
|
Malignant neoplasm of prostate
|
0.340 |
AlteredExpression
|
disease |
BEFREE |
In the present study, it was observed that CX3CL1/C-X3-C motif chemokine receptor 1 (CX3CR1) was overexpressed in prostate cancer tissues with spinal metastasis compared with primary tumors.
|
30066854 |
2018 |