Diabetes Mellitus, Experimental
|
0.500 |
Biomarker
|
disease |
CTD_human |
Inflammation and apoptosis in aortic tissues of aged type II diabetes: amelioration with alpha-lipoic acid through phosphatidylinositol 3-kinase/Akt- dependent mechanism.
|
20388520 |
2010 |
Diabetes Mellitus, Experimental
|
0.500 |
Biomarker
|
disease |
RGD |
Fractalkine and its receptor, CX3CR1, upregulation in streptozotocin-induced diabetic kidneys.
|
15153757 |
2004 |
Malignant neoplasm of prostate
|
0.340 |
AlteredExpression
|
disease |
BEFREE |
After the exclusion of men with conditions linked with systemic inflammation, associations between prostate cancer and deviant levels of C-X3-C motif chemokine ligand 1, platelet-derived growth factor subunit B homodimer, interleukin 10, C-C motif chemokine ligand (CCL) 21, and CCL11 remained statistically significant.
|
31212389 |
2019 |
Malignant neoplasm of prostate
|
0.340 |
AlteredExpression
|
disease |
BEFREE |
In the present study, it was observed that CX3CL1/C-X3-C motif chemokine receptor 1 (CX3CR1) was overexpressed in prostate cancer tissues with spinal metastasis compared with primary tumors.
|
30066854 |
2018 |
Malignant neoplasm of prostate
|
0.340 |
Biomarker
|
disease |
BEFREE |
These findings revealed that CX3CL1 may serve as a new target for the treatment of prostate cancer.
|
26718770 |
2016 |
Malignant neoplasm of prostate
|
0.340 |
Biomarker
|
disease |
BEFREE |
CX3CR1 has also shown to be involved in the homing to specific tissues that express the ligand, CX3CL1, in breast and prostate cancer and may thus be involved in dissemination of lymphoma.
|
18060687 |
2008 |
Malignant neoplasm of prostate
|
0.340 |
Biomarker
|
disease |
CTD_human |
Global analysis of differentially expressed genes in androgen-independent prostate cancer.
|
17199135 |
2007 |
Prostatic Neoplasms
|
0.310 |
Biomarker
|
group |
LHGDN |
Membrane microvesicles as actors in the establishment of a favorable prostatic tumoral niche: a role for activated fibroblasts and CX3CL1-CX3CR1 axis.
|
19155311 |
2009 |
Prostatic Neoplasms
|
0.310 |
Biomarker
|
group |
CTD_human |
Global analysis of differentially expressed genes in androgen-independent prostate cancer.
|
17199135 |
2007 |
Hypersensitivity
|
0.300 |
Biomarker
|
group |
CTD_human |
Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression.
|
21625544 |
2011 |
Pneumonia
|
0.300 |
Biomarker
|
disease |
CTD_human |
Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression.
|
21625544 |
2011 |
Lobar Pneumonia
|
0.300 |
Biomarker
|
disease |
CTD_human |
Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression.
|
21625544 |
2011 |
Experimental Lung Inflammation
|
0.300 |
Biomarker
|
disease |
CTD_human |
Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression.
|
21625544 |
2011 |
Allergic Reaction
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression.
|
21625544 |
2011 |
Pneumonitis
|
0.300 |
Biomarker
|
disease |
CTD_human |
Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression.
|
21625544 |
2011 |
Alloxan Diabetes
|
0.300 |
Biomarker
|
disease |
CTD_human |
Inflammation and apoptosis in aortic tissues of aged type II diabetes: amelioration with alpha-lipoic acid through phosphatidylinositol 3-kinase/Akt- dependent mechanism.
|
20388520 |
2010 |
Streptozotocin Diabetes
|
0.300 |
Biomarker
|
disease |
CTD_human |
Inflammation and apoptosis in aortic tissues of aged type II diabetes: amelioration with alpha-lipoic acid through phosphatidylinositol 3-kinase/Akt- dependent mechanism.
|
20388520 |
2010 |
Myocardial Ischemia
|
0.300 |
Biomarker
|
disease |
CTD_human |
Cardioplegia prevents ischemia-induced transcriptional alterations of cytoprotective genes in rat hearts: a DNA microarray study.
|
16214533 |
2005 |
Uveitis
|
0.210 |
AlteredExpression
|
disease |
BEFREE |
The levels of all neutrophil chemoattractants and CXCL10, CXCL16, and CX3CL1 were significantly higher in nongranulomatous uveitis (Behçet's disease and HLA-B27-associated uveitis) than in granulomatous uveitis (sarcoidosis and VKH disease), whereas the levels of the B cell chemoattractant CXCL13 were significantly higher in granulomatous uveitis than in nongranulomatous uveitis.
|
29715366 |
2018 |
Hyperalgesia
|
0.210 |
AlteredExpression
|
phenotype |
BEFREE |
Because chemokine fractalkine (CX3CL1) has been suggested as an important signal during neuropathic pain development, this study aimed to investigate whether CX3CL1 expression may be modulated by EGCG treatment reducing hyperalgesia in chronic constriction injured mice.
|
27896922 |
2017 |
Myocarditis
|
0.210 |
Biomarker
|
disease |
BEFREE |
These findings demonstrate a cardioprotective role of CX3CR1 in CVB3-infected mice and indicate the relevance of the CX3CL1/CX3CR1 system in CVB3-induced myocarditis.
|
28800592 |
2017 |
Hyperalgesia
|
0.210 |
Therapeutic
|
phenotype |
RGD |
Gabapentin reduces CX3CL1 signaling and blocks spinal microglial activation in monoarthritic rats.
|
22647647 |
2012 |
Endotoxemia
|
0.210 |
Biomarker
|
phenotype |
BEFREE |
Endotoxemia induced adipose CX3CL1 mRNA (32.7-fold, P < 1 × 10(-5)) and protein (43-fold, P = 0.006).
|
21525510 |
2011 |
Hyperalgesia
|
0.210 |
Biomarker
|
phenotype |
RGD |
Role of spinal microglia in visceral hyperalgesia and NK1R up-regulation in a rat model of chronic stress.
|
19249394 |
2009 |
Uveitis
|
0.210 |
Biomarker
|
disease |
RGD |
Expression of fractalkine (CX3CL1) and its receptor in endotoxin-induced uveitis.
|
19648777 |
2009 |