SFTPB, surfactant protein B, 6439

N. diseases: 108; N. variants: 11
Disease: Pneumonia, Bacterial ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004626
Disease: Pneumonia, Bacterial
Pneumonia, Bacterial 		0.220 GeneticVariation group BEFREE Our hypothesis is that functional differences of SP-B variants and treatment with curcumin (CMC2.24) modulate lung injury in bacterial pneumonia. 26863117 2016
CUI: C0004626
Disease: Pneumonia, Bacterial
Pneumonia, Bacterial 		0.220 GeneticVariation group BEFREE This study aimed to generate humanized SP-B transgenic mice carrying either SP-B C or T allele without a mouse SP-B background and then examine functional susceptibility to bacterial pneumonia in vivo. 26620227 2016
CUI: C0004626
Disease: Pneumonia, Bacterial
Pneumonia, Bacterial 		0.220 Biomarker group RGD Total extracellular surfactant is increased but abnormal in a rat model of gram-negative bacterial pneumonia. 12169586 2002