SFTPC, surfactant protein C, 6440

N. diseases: 132; N. variants: 14
Disease: Pneumonia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032285
Disease: Pneumonia
Pneumonia 		0.130 Biomarker disease BEFREE To determine if pulmonary inflammation is sufficient to cause adverse cardiometabolic effects, SFTPC-rtTA+/-tetO-cre+/-pROSA-inhibitor κB kinase 2(IKK2)ca+/- (LungIKK2ca) and littermate SFTPC-rtTA+/-tetO-cre-/-pROSA-IKK2ca+/- wildtype (WT) mice were fed with doxycycline diet to induce constitutively active Ikk2 (Ikk2ca) overexpression in the lung and their pulmonary, systemic, adipose, and hypothalamic inflammations, vascular function, and glucose homeostasis were assessed. 29036520 2017
CUI: C0032285
Disease: Pneumonia
Pneumonia 		0.130 Biomarker disease BEFREE Persistence of LPS-induced lung inflammation in surfactant protein-C-deficient mice. 23795648 2013
CUI: C0032285
Disease: Pneumonia
Pneumonia 		0.130 Biomarker disease BEFREE SP-C deficiency increases the severity of RSV-induced pulmonary inflammation through regulation of TLR3 signaling. 19304906 2009
CUI: C0032285
Disease: Pneumonia
Pneumonia 		0.130 Biomarker disease HPO