Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Familial hypercholesterolemia - heterozygous
0.010 Biomarker disease BEFREE To assess the feasibility of detecting new cases of heterozygous familial hypercholesterolaemia by using a nurse led genetic register. 11118175 2000
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.020 Biomarker disease BEFREE The present study investigated the effects of the miR‑195-led gene pathway in the sensitization of breast cancer cells to treatment with the chemotherapeutic drug Adriamycin. 23760062 2013
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.020 Biomarker disease BEFREE The present study investigated the effects of the miR‑195-led gene pathway in the sensitization of breast cancer cells to treatment with the chemotherapeutic drug Adriamycin. 23760062 2013
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.040 Biomarker group BEFREE This study further demonstrated that targeting of the altered RARβ₂-led gene pathway could effectively suppress the development of this deadly type of cancer. 23812217 2014
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.040 Biomarker group BEFREE This study further demonstrated that targeting of the altered RARβ₂-led gene pathway could effectively suppress the development of this deadly type of cancer. 23812217 2014
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme
0.010 Biomarker disease BEFREE In conclusion, small molecule inhibitor-led targeting of Axl may be a promising therapy for GBM progression. 25980499 2015
CUI: C0079731
Disease: B-Cell Lymphomas
B-Cell Lymphomas
0.010 Biomarker group BEFREE The present study was performed to examine the induction of apoptotic cell death and autophagy by blue LED irradiation, and the contribution of autophagy to apoptosis in B cell lymphoma A20 and RAMOS cells exposed to blue LED. 26555754 2016
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation
0.010 Biomarker disease BEFREE In this trial, we evaluated a novel App for its accuracy to differentiate between patients in AF and patients in sinus rhythm (SR) using the plethysmographic sensor of an iPhone 4S and the integrated LED only. 27371660 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.030 Biomarker group BEFREE We used Nicolet Endeavour CR IOM (Carefusion, Middleton WI, USA) to performed visual evoked potentials stimulating binocularly with LED flash goggles with the patient´s eyes closed and direct epidural optic nerve stimulation delivering rostral to the tumor a rectangular current pulse. 27586244 2017
CUI: C0002871
Disease: Anemia
Anemia
0.010 Biomarker disease BEFREE LED/SOF with RBV showed a worse safety profile when compared with LED/SOF without RBV for the following outcomes: any AE (RR 0.56 [95% CI 0.46-0.69]), anemia (RR 0.08 [95% CI 0.04-0.17]), and rash (RR 0.35 [95% CI 0.19-0.65]). 27785825 2017
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.010 GeneticVariation disease BEFREE Ledipasvir with sofosbuvir (LED/SOF) for the treatment of patients infected with genotype 1 hepatitis C virus can be used with or without ribavirin (RBV). 27785825 2017
CUI: C0035851
Disease: Root Resorption
Root Resorption
0.020 Biomarker disease BEFREE We aimed to identify a minimal dose-response relationship to LED therapy with regard to orthodontic tooth movement (OTM) and root resorption in rats. 27796672 2017
CUI: C0344323
Disease: Flashing
Flashing
0.030 Biomarker disease BEFREE We collected verbal pain ratings of laser stimuli from participants following 10 minutes of flashing LED goggle stimulation and 10 minutes of binaural beat stimulation across the alpha range. 27807916 2017
CUI: C0085635
Disease: Photopsia
Photopsia
0.020 Biomarker phenotype BEFREE For development of the proposed sensor, we utilize the ambient light sensor (ALS) of the smartphone as light intensity detector and its LED flash light as an optical source. 27982569 2017
CUI: C0085635
Disease: Photopsia
Photopsia
0.020 Biomarker phenotype BEFREE Based on the opponent theory of colour vision, this study used 32 Hz/40 Hz rectangular red-green or red-blue LED light pulses with a 50% duty cycle, balanced/equal luminance and 0°/180° phase shifts as the stimulating light sources and tested their efficacy in producing SSVEP responses with high signal-to-noise ratios (SNRs) while reducing the perceived flickering sensation. 28000607 2017
CUI: C0041296
Disease: Tuberculosis
Tuberculosis
0.010 Biomarker disease BEFREE Hence, we assessed the diagnostic performance of Loop-mediated isothermal amplification (LAMP) assay in detecting M.tuberculosis infection in sputum sample compared to LED fluorescent smear microscopy and culture. 28095790 2017
CUI: C1609538
Disease: Latent Tuberculosis
Latent Tuberculosis
0.010 Biomarker disease BEFREE Hence, we assessed the diagnostic performance of Loop-mediated isothermal amplification (LAMP) assay in detecting M.tuberculosis infection in sputum sample compared to LED fluorescent smear microscopy and culture. 28095790 2017
CUI: C0015967
Disease: Fever
Fever
0.040 Biomarker phenotype BEFREE In addition, real-time temperature monitoring demonstrated that the rGO films could act as an excellent thermal dissipation material in LED packages by reducing 10%-15% of the temperature increase. 28139800 2017
CUI: C0015397
Disease: Disorder of eye
Disorder of eye
0.010 Biomarker group BEFREE To present the experience of eye fundus photo documentation by using the plus 20 diopters spherical Volk lens and a smartphone with 4.2 Mpix camera and LED flash within the screening project of eye disorders in countries where the standard ophthalmology equipment is not available. 28149793 2017
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.040 AlteredExpression group BEFREE Upregulation of LINC0086 inhibited cancer cell proliferation and promoted apoptosis. 28245169 2017
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.040 AlteredExpression group BEFREE Upregulation of LINC0086 inhibited cancer cell proliferation and promoted apoptosis. 28245169 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.030 Biomarker group BEFREE Long Noncoding RNA LINC0086 Functions as a Tumor Suppressor in Nasopharyngeal Carcinoma by Targeting miR-214. 28245169 2017
CUI: C2931822
Disease: Nasopharyngeal carcinoma
Nasopharyngeal carcinoma
0.010 AlteredExpression disease BEFREE LINC0086 expression was associated with NPC histological grade, lymph node metastasis, and clinical stage. 28245169 2017
CUI: C0024530
Disease: Malaria
Malaria
0.020 Biomarker disease BEFREE In order to assess the effectiveness of LED fluorescence microscopy in malaria diagnosis, a cross-sectional study was conducted at a tertiary care teaching hospital in Mumbai. 28279619 2018
CUI: C0024530
Disease: Malaria
Malaria
0.020 Biomarker disease BEFREE Malaria over-diagnosis in Cameroon: diagnostic accuracy of Fluorescence and Staining Technologies (FAST) Malaria Stain and LED microscopy versus Giemsa and bright field microscopy validated by polymerase chain reaction. 28372570 2017