|
Chronic Lymphocytic Leukemia
|
0.300 |
Biomarker
|
disease |
CTD_human |
Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk.
|
20062064 |
2010 |
|
Glioblastoma
|
0.220 |
Biomarker
|
disease |
BEFREE |
miR‑454‑3p suppresses cell migration and invasion by targeting CPEB1 in human glioblastoma.
|
30106109 |
2018 |
|
Adult Glioblastoma
|
0.220 |
Biomarker
|
disease |
BEFREE |
miR‑454‑3p suppresses cell migration and invasion by targeting CPEB1 in human glioblastoma.
|
30106109 |
2018 |
|
Glioblastoma
|
0.220 |
ModifyingMutation
|
disease |
RGD |
Our findings show that CPEB1 is hyperactive in rat glioblastoma cells and is regulating an important cohort of mRNAs whose increased translation is fueling the progression of tumor proliferation and dispersal in the brain.
|
23360795 |
2013 |
|
Glioblastoma
|
0.220 |
Biomarker
|
disease |
BEFREE |
Our findings show that CPEB1 is hyperactive in rat glioblastoma cells and is regulating an important cohort of mRNAs whose increased translation is fueling the progression of tumor proliferation and dispersal in the brain.
|
23360795 |
2013 |
|
Adult Glioblastoma
|
0.220 |
Biomarker
|
disease |
BEFREE |
Our findings show that CPEB1 is hyperactive in rat glioblastoma cells and is regulating an important cohort of mRNAs whose increased translation is fueling the progression of tumor proliferation and dispersal in the brain.
|
23360795 |
2013 |
|
Adult Glioblastoma
|
0.220 |
ModifyingMutation
|
disease |
RGD |
Our findings show that CPEB1 is hyperactive in rat glioblastoma cells and is regulating an important cohort of mRNAs whose increased translation is fueling the progression of tumor proliferation and dispersal in the brain.
|
23360795 |
2013 |
|
Portal Hypertension
|
0.210 |
Biomarker
|
disease |
RGD |
Sequential Functions of CPEB1 and CPEB4 Regulate Pathologic Expression of Vascular Endothelial Growth Factor and Angiogenesis in Chronic Liver Disease.
|
26627607 |
2016 |
|
Portal Hypertension
|
0.210 |
Biomarker
|
disease |
BEFREE |
In a search for ways to inhibit pathologic production or activities of VEGF without affecting its normal production or functions, we investigated the post-transcriptional regulation of VEGF by the cytoplasmic polyadenylation element-binding proteins CPEB1 and CPEB4 during development of portal hypertension and liver disease.
|
26627607 |
2016 |
|
Primary biliary cirrhosis
|
0.200 |
Biomarker
|
disease |
RGD |
Sequential Functions of CPEB1 and CPEB4 Regulate Pathologic Expression of Vascular Endothelial Growth Factor and Angiogenesis in Chronic Liver Disease.
|
26627607 |
2016 |
|
Biliary cirrhosis
|
0.200 |
Biomarker
|
disease |
RGD |
Sequential Functions of CPEB1 and CPEB4 Regulate Pathologic Expression of Vascular Endothelial Growth Factor and Angiogenesis in Chronic Liver Disease.
|
26627607 |
2016 |
|
Glioblastoma, IDH-Wildtype
|
0.200 |
ModifyingMutation
|
disease |
RGD |
CPEB1 regulates the expression of MTDH/AEG-1 and glioblastoma cell migration.
|
23360795 |
2013 |
|
Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Intelligence
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.
|
31374203 |
2019 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.
|
30285260 |
2019 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.
|
31374203 |
2019 |
|
Intelligence
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.
|
29844566 |
2018 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia.
|
28991256 |
2017 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study of schizophrenia in Ashkenazi Jews.
|
26198764 |
2015 |
|
Serum albumin measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
A genome-wide assessment of variability in human serum metabolism.
|
23281178 |
2013 |
|
Neoplasms
|
0.070 |
Biomarker
|
group |
BEFREE |
Multivariate Cox proportional hazards model showed that high CPEB1 (P=0.027), low CPEB4 expressions (P=0.021), and advanced tumor grade (P=0.036) were independent predictor of overall survival.
|
27000226 |
2016 |
|
Neoplasms
|
0.070 |
AlteredExpression
|
group |
BEFREE |
Decreased expression of CPEB1 protein in gliomas correlated with the rising grade of tumor malignancy.
|
27256982 |
2016 |
|
Neoplasms
|
0.070 |
Biomarker
|
group |
BEFREE |
Indeed, wild-type miR-455-5p promotes melanoma metastasis through inhibition of the tumour suppressor gene CPEB1.
|
25686251 |
2015 |
|
Neoplasms
|
0.070 |
Biomarker
|
group |
BEFREE |
CPEB1 is also regulated directly by the tumor suppressor miR-101, a potential marker of glioma.
|
23788032 |
2013 |
|
Neoplasms
|
0.070 |
Biomarker
|
group |
BEFREE |
Our findings show that CPEB1 is hyperactive in rat glioblastoma cells and is regulating an important cohort of mRNAs whose increased translation is fueling the progression of tumor proliferation and dispersal in the brain.
|
23360795 |
2013 |