Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1850127
Disease: Osteopetrosis, Autosomal Recessive 1
Osteopetrosis, Autosomal Recessive 1 		0.200 Biomarker disease MGD A new osteopetrosis mutant mouse strain (ntl) with odontoma-like proliferations and lack of tooth roots. 20121924 2009
CUI: C4551971
Disease: Albers-Schonberg Disease, Autosomal Recessive
Albers-Schonberg Disease, Autosomal Recessive 		0.200 Biomarker disease MGD A new osteopetrosis mutant mouse strain (ntl) with odontoma-like proliferations and lack of tooth roots. 20121924 2009
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		0.010 Biomarker disease BEFREE Coiled-coil domain-containing protein 154 (CCDC154) and tripartite motif-containing protein 3 (TRIM3) were key proteins involved in the molecular mechanisms of PD, participating in intracellular vesicle, ubiquitin protein ligase and transition metal ion-binding activities. 31572530 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.010 Biomarker group BEFREE CCDC154 also inhibited tumor cell growth, and the soft agar assay revealed a significant decrease of the colony size of Hela cells upon transfection of CCDC154. 22895184 2012
CUI: C0029454
Disease: Osteopetrosis
Osteopetrosis 		0.010 Biomarker disease BEFREE Our results indicate that CCDC154 is a novel osteopetrosis-related gene involved in cell cycle regulation and tumor suppression growth. 22895184 2012