SHBG, sex hormone binding globulin, 6462

N. diseases: 368; N. variants: 20
Disease: Metabolic Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025517
Disease: Metabolic Diseases
Metabolic Diseases 		0.050 Biomarker group BEFREE Given known associations of low SHBG and FSH with cardio-metabolic disease, the clinical implications of hormonal changes by cirrhosis severity in HCV-infected women warrants investigation. 30339729 2019
CUI: C0025517
Disease: Metabolic Diseases
Metabolic Diseases 		0.050 Biomarker group BEFREE Follicle stimulating hormone plays direct roles in a variety of nongonadal tissues and sex hormone binding globulin is becoming the convergence of the crosstalk among metabolic diseases. 28260206 2017
CUI: C0025517
Disease: Metabolic Diseases
Metabolic Diseases 		0.050 Biomarker group BEFREE In conclusion, lower serum SHBG is associated with a higher prevalence of NAFLD, compared with MS and other metabolic disorders, in T2D patients. 29109457 2017
CUI: C0025517
Disease: Metabolic Diseases
Metabolic Diseases 		0.050 Biomarker group BEFREE Sex Hormone-Binding Globulin Reduction in Metabolic Disorders May Play a Role in NAFLD Development. 28359088 2017
CUI: C0025517
Disease: Metabolic Diseases
Metabolic Diseases 		0.050 AlteredExpression group BEFREE These important advances in our knowledge of the regulation of SHBG expression in the liver open new approaches for identifying and preventing metabolic disorder-associated diseases early in life. 19786070 2010