EBF2, EBF transcription factor 2, 64641

N. diseases: 27; N. variants: 12
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
0.030 AlteredExpression disease BEFREE Our research indicated that downexpression of miR-182-3p in OS cells results in overexpression of EBF2 and promotes the progression of OS. 30993113 2019
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
0.030 AlteredExpression disease BEFREE Additionally, EBF2 overexpression rescued the phenotype caused by miR-204-5p.Our data indicated that miR-204-5p is an anti-oncogenic miRNA in osteosarcoma which functions through inhibiting oncogenic transcription factor EBF2. 30529043 2019
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
0.030 AlteredExpression disease BEFREE EBF2 up-regulation may be one of the mechanisms involved in the high levels of OPG in osteosarcoma, contributing to decrease TRAIL-induced apoptosis and leading to TRAIL resistance. 19671856 2009