Malignant neoplasm of breast
|
0.320 |
GeneticVariation
|
disease |
UNIPROT |
|
|
|
Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits.
|
28552196 |
2017 |
Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
|
20881960 |
2010 |
Smoking
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
GWAS and systems biology analysis of depressive symptoms among smokers from the COPDGene cohort.
|
30219690 |
2019 |
Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
|
20881960 |
2010 |
Major Depressive Disorder
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
GWAS and systems biology analysis of depressive symptoms among smokers from the COPDGene cohort.
|
30219690 |
2019 |
Epilepsy, Lateral Temporal
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Mutations in MICAL-1cause autosomal-dominant lateral temporal epilepsy.
|
29394500 |
2018 |
Malignant neoplasm of breast
|
0.320 |
Biomarker
|
disease |
BEFREE |
Herein, we tested whether MICAL1 could control cell migration and invasion through regulating ROS in breast cancer cell lines.
|
27430308 |
2016 |
Malignant neoplasm of breast
|
0.320 |
Biomarker
|
disease |
BEFREE |
We noticed that depletion of MICAL1 markedly reduced cell proliferation in breast cancer cell line MCF-7 and T47D.
|
29524295 |
2018 |
Epilepsy, Familial Temporal Lobe 1
|
0.300 |
Biomarker
|
disease |
CTD_human |
|
|
|
Complex partial seizures
|
0.100 |
Biomarker
|
disease |
HPO |
|
|
|
Simple Partial Seizures
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
Complex partial seizure with impairment of consciousness
|
0.100 |
Biomarker
|
disease |
HPO |
|
|
|
Generalized tonic-clonic seizures with focal onset
|
0.100 |
Biomarker
|
disease |
HPO |
|
|
|
Focal sensory auditory seizure
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
Malignant Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
In sum, this study identified novel effectors that mediate the pro-migratory role of TGF-β signaling, paving the way for future studies that investigate the function of MICAL family members in cancer and the novel epigenetic mechanisms downstream TGF-β signaling.
|
31449970 |
2019 |
Malignant Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
Molecules Interacting with CasL (MICAL1), a multidomain flavoprotein monoxygenase, is strongly involved in the mechanisms that promote cancer cell proliferation and survival.
|
27430308 |
2016 |
Breast Carcinoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Herein, we tested whether MICAL1 could control cell migration and invasion through regulating ROS in breast cancer cell lines.
|
27430308 |
2016 |
Breast Carcinoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
We noticed that depletion of MICAL1 markedly reduced cell proliferation in breast cancer cell line MCF-7 and T47D.
|
29524295 |
2018 |
Tumor Cell Invasion
|
0.020 |
Biomarker
|
phenotype |
BEFREE |
Recently, results from our laboratory have shown that MICAL1 modulates reactive oxygen species (ROS) production, and the latter then activates phosphatidyl inositol 3-kinase (PI3K)/protein kinase B (Akt) signalling pathway which regulates breast cancer cell invasion.
|
29524295 |
2018 |
Tumor Cell Invasion
|
0.020 |
Biomarker
|
phenotype |
BEFREE |
Herein, we tested whether MICAL1 could control cell migration and invasion through regulating ROS in breast cancer cell lines.
|
27430308 |
2016 |
Primary malignant neoplasm
|
0.020 |
Biomarker
|
group |
BEFREE |
Molecules Interacting with CasL (MICAL1), a multidomain flavoprotein monoxygenase, is strongly involved in the mechanisms that promote cancer cell proliferation and survival.
|
27430308 |
2016 |
Primary malignant neoplasm
|
0.020 |
Biomarker
|
group |
BEFREE |
In sum, this study identified novel effectors that mediate the pro-migratory role of TGF-β signaling, paving the way for future studies that investigate the function of MICAL family members in cancer and the novel epigenetic mechanisms downstream TGF-β signaling.
|
31449970 |
2019 |
Epilepsy
|
0.010 |
Biomarker
|
disease |
BEFREE |
Thus, as an effect factor participated in F-actin disassemble, Mical-1 may associate with inner pathophysiological modulation in epilepsy.
|
21638339 |
2011 |
Epilepsy, Temporal Lobe
|
0.010 |
Biomarker
|
disease |
BEFREE |
Faint and scattered immunoreactivity for Mical-1 in the neuron of temporal neocortex in TLE group, but strong immunoreactivity for Mical-1 was shown in control subjects.
|
21638339 |
2011 |