BMP1, bone morphogenetic protein 1, 649

N. diseases: 121; N. variants: 17
Disease: Impaired cognition ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.030 Biomarker disease BEFREE Synaptic biomarker reduction and impaired cognition in the sub-chronic PCP mouse model for schizophrenia. 31580184 2020
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.030 Biomarker disease BEFREE Vortioxetine Treatment Reverses Subchronic PCP Treatment-Induced Cognitive Impairments: A Potential Role for Serotonin Receptor-Mediated Regulation of GABA Neurotransmission. 29559911 2018
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.030 Biomarker disease BEFREE We conclude that acute PCP induces SCZ-like symptom classes in a dose-dependent manner; PCP doses of 1.0-2.0 mg/kg are more suitable for modeling SCZ-like negative symptoms and cognitive deficits, while SCZ-like positive symptoms dominate at doses of 3.0-5.0 mg/kg. 28342897 2017