SIX1, SIX homeobox 1, 6495

N. diseases: 200; N. variants: 12
Disease: Nephroblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027708
Disease: Nephroblastoma
Nephroblastoma 		0.310 Biomarker disease CTD_human A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor. 28825729 2017
CUI: C0027708
Disease: Nephroblastoma
Nephroblastoma 		0.310 Biomarker disease BEFREE In this study, we investigate the mechanism by which the Six1 homeobox protein, which has a crucial role during development, is frequently deregulated in several poor outcome, aggressive, metastatic adult human cancers, including breast cancer, ovarian cancer, hepatocellular carcinoma and pediatric malignancies such as rhabdomyosarcoma and Wilms' tumor. 20603620 2010