BMP4, bone morphogenetic protein 4, 652

N. diseases: 423; N. variants: 21
Disease: Cleft palate with cleft lip ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0158646
Disease: Cleft palate with cleft lip
Cleft palate with cleft lip 		0.320 GeneticVariation disease BEFREE BMP2 and BMP4 variations and risk of non-syndromic cleft lip and palate. 27591802 2016
CUI: C0158646
Disease: Cleft palate with cleft lip
Cleft palate with cleft lip 		0.320 SusceptibilityMutation disease ORPHANET Evaluating rare coding variants as contributing causes to non-syndromic cleft lip and palate. 22978696 2013
CUI: C0158646
Disease: Cleft palate with cleft lip
Cleft palate with cleft lip 		0.320 Biomarker disease BEFREE Combining the results of chromosomal linkage studies of unidentified human CLP genes with insights from the mouse models, the following previously unexamined genes are identified as strong candidate genes for causative roles in human nonsyndromic CLP: BMP4, BMPR1B, TFAP2A, SOX4, WNT9B, WNT3, and SP8. 18181213 2008