SLC5A5, solute carrier family 5 member 5, 6528

N. diseases: 195; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.360 AlteredExpression group BEFREE Interestingly, NIS protein level was correlated with MEK/ERK activation in human breast tumors from a tissue microarray. 23404856 2013
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.360 AlteredExpression group BEFREE The sodium-iodide symporter (NIS), which mediates iodide uptake into thyroid cells, and is the molecular basis of radioiodine imaging and therapy in thyroid cancer, is also expressed in a large portion of breast tumors. 20213084 2010
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.360 AlteredExpression group LHGDN Enhancement of sodium/iodide symporter expression in thyroid and breast cancer. 16954431 2006
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.360 AlteredExpression group LHGDN Signaling through 3',5'-cyclic adenosine monophosphate and phosphoinositide-3 kinase induces sodium/iodide symporter expression in breast cancer. 15472226 2004
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.360 AlteredExpression group LHGDN We report high NIS expression at both transcriptional and translational level and its ability to transport iodine in human breast tumors. 12602914 2003
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.360 Therapeutic group CTD_human The rat sodium iodide symporter gene permits more effective radioisotope concentration than the human sodium iodide symporter gene in human and rodent cancer cells. 12489024 2003
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.360 PosttranslationalModification group BEFREE Correlation between 99mTc-pertechnetate uptakes and expressions of human sodium iodide symporter gene in breast tumor tissues. 11578905 2001