Unipolar Depression
|
0.400 |
Biomarker
|
disease |
BEFREE |
The authors tested norepinephrine transporter availability in patients with major depressive disorder with the aim to identify any associations between test results and clinical symptoms.
|
27631962 |
2017 |
Unipolar Depression
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
This study attempted to examine the relationship between polymorphisms of NET gene and MD.
|
26061302 |
2015 |
Unipolar Depression
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
This study suggests that the investigated polymorphisms in the NET gene are not major risk factors in increasing susceptibility to either major depression or its clinical subtypes in a Han Chinese population.
|
17353941 |
2007 |
Unipolar Depression
|
0.400 |
Biomarker
|
disease |
BEFREE |
The norepinephrine transporter gene modulates the relationship between urban/rural residency and major depressive disorder in a Chinese population.
|
19564048 |
2009 |
Unipolar Depression
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The NET T-182C polymorphism may be in part related to the pathophysiology of major depressive disorder in a Japanese population.
|
15539861 |
2004 |
Unipolar Depression
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Association between T-182C, G1287A polymorphism in NET gene and suicidality in major depressive disorder in Chinese patients.
|
29703117 |
2018 |
Unipolar Depression
|
0.400 |
Biomarker
|
disease |
BEFREE |
These results suggest that the NET gene is unlikely to be involved in the susceptibility to major depression.
|
10512149 |
1999 |
Unipolar Depression
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The present study suggests that the combined effect of rs2242446 and rs5569 in the NET gene could modify the response to the negative life events in triggering MD.
|
18779921 |
2008 |
Unipolar Depression
|
0.400 |
PosttranslationalModification
|
disease |
BEFREE |
Methylation of the SLC6a2 gene promoter in major depression and panic disorder.
|
24312678 |
2013 |
Unipolar Depression
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Association between norepinephrine transporter T-182C polymorphism and major depressive disorder: a meta-analysis.
|
24374057 |
2014 |
Unipolar Depression
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Association between major depressive disorder and the norepinephrine transporter polymorphisms T-182C and G1287A: a meta-analysis.
|
23648227 |
2013 |
Unipolar Depression
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Relationship between G1287A of the NET Gene Polymorphisms and Brain Volume in Major Depressive Disorder: A Voxel-Based MRI Study.
|
26960194 |
2016 |
Unipolar Depression
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
252 unrelated Caucasian patients (f = 142; m = 110) with major depression were genotyped for NET and 5-HTT polymorphisms.
|
20588071 |
2010 |
Unipolar Depression
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The sample comprised 426 patients suffering from unipolar MD as well as 643 healthy control subjects for the variants of the 5-HT(1A) receptor and the NET.
|
19105200 |
2009 |
Unipolar Depression
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
No association of the G1287A polymorphism in the norepinephrine transporter gene and susceptibility to major depressive disorder in a Japanese population.
|
17917281 |
2007 |
Unipolar Depression
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Therefore, we investigated whether the T-182C polymorphism of the NET gene is associated with major depression in a Korean sample of 112 major depression patients compared with 136 healthy controls.
|
15118352 |
2004 |
Unipolar Depression
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
In self-identified white patients with major depressive disorder (N=126) treated with open-label duloxetine (60-120 mg/d), a significant association of (P=0.020) of a composite risk score (based on SLC6A2 rs5569 [G1287A] AA, HTR1A rs6295 [C(-1019)G] GG, and COMT rs174697 AA/AG) with 17-item Hamilton Depression Rating Scale total score change from baseline to 12 weeks was observed.
|
22727709 |
2012 |
Unipolar Depression
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
In a case control association study we investigated the newly identified T-182C polymorphism and an already known G1287A polymorphism in exon 9 of the NET gene in a sample of 193 patients with major depression and 136 healthy, non-related controls.
|
11927173 |
2002 |
Unipolar Depression
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
SLC6A2 variants may predict remission from major depression after venlafaxine treatment in Han Chinese population.
|
25512257 |
2015 |
Unipolar Depression
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
We conducted an 8-week, open-label, prospective pilot study in 35 patients with major depressive disorder to assess the effects of genetic variations in SLC6A2 and SLC6A4 on both efficacy and side effect profile of desvenlafaxine.
|
27023264 |
2016 |
Unipolar Depression
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
NET rs2242446/T-182C may serve as a biomarker to predict the likelihood of remission with venlafaxine in older adults with major depression.
|
28068779 |
2017 |
Unipolar Depression
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Association between norepinephrine transporter gene (SLC6A2) polymorphisms and suicide in patients with major depressive disorder.
|
24655776 |
2014 |
Unipolar Depression
|
0.400 |
Biomarker
|
disease |
BEFREE |
This study demonstrates that clinically relevant doses of venlafaxine extended-release block the norepinephrine transporter of the major depressive disorder patient's brain.
|
30649319 |
2019 |
Unipolar Depression
|
0.400 |
Biomarker
|
disease |
PSYGENET |
Association between norepinephrine transporter gene (SLC6A2) polymorphisms and suicide in patients with major depressive disorder.
|
24655776 |
2014 |
Unipolar Depression
|
0.400 |
Biomarker
|
disease |
PSYGENET |
SLC6A2 variants may predict remission from major depression after venlafaxine treatment in Han Chinese population.
|
25512257 |
2015 |