SLC6A3, solute carrier family 6 member 3, 6531

N. diseases: 373; N. variants: 38
Disease: Cocaine Abuse ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.520 Biomarker disease PSYGENET Dopamine transporter DAT and receptor DRD2 variants affect risk of lethal cocaine abuse: a gene-gene-environment interaction. 23340505 2013
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.520 Biomarker disease BEFREE Dopamine transporter DAT and receptor DRD2 variants affect risk of lethal cocaine abuse: a gene-gene-environment interaction. 23340505 2013
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.520 Biomarker disease PSYGENET However, in a previous study, DAT knockout mice were reported to self-administer cocaine, generating much debate regarding the importance of the DAT in cocaine's abuse-related effects. 19602552 2009
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.520 Biomarker disease CTD_human However, in a previous study, DAT knockout mice were reported to self-administer cocaine, generating much debate regarding the importance of the DAT in cocaine's abuse-related effects. 19602552 2009
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.520 Therapeutic disease CTD_human However, in a previous study, DAT knockout mice were reported to self-administer cocaine, generating much debate regarding the importance of the DAT in cocaine's abuse-related effects. 19602552 2009
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.520 Biomarker disease CTD_human A dopamine transporter gene functional variant associated with cocaine abuse in a Brazilian sample. 16537431 2006
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.520 GeneticVariation disease BEFREE A dopamine transporter gene functional variant associated with cocaine abuse in a Brazilian sample. 16537431 2006
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.520 Biomarker disease PSYGENET A dopamine transporter gene functional variant associated with cocaine abuse in a Brazilian sample. 16537431 2006
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.520 Therapeutic disease CTD_human A dopamine transporter gene functional variant associated with cocaine abuse in a Brazilian sample. 16537431 2006
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.520 Biomarker disease CTD_human Self-administration of cocaine and the cocaine analog RTI-113: relationship to dopamine transporter occupancy determined by PET neuroimaging in rhesus monkeys. 11746736 2002
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.520 Therapeutic disease CTD_human Self-administration of cocaine and the cocaine analog RTI-113: relationship to dopamine transporter occupancy determined by PET neuroimaging in rhesus monkeys. 11746736 2002
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.520 Therapeutic disease CTD_human Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference. 11320258 2001
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.520 Biomarker disease CTD_human Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference. 11320258 2001
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.520 Biomarker disease PSYGENET The effects of chronic cocaine abuse on transcriptional regulation of human dopamine transporter (DAT) mRNA in midbrain dopaminergic neurons was assessed by reverse transcription-polymerase chain reaction (RT-PCR). 10581411 1999