SLC6A3, solute carrier family 6 member 3, 6531

N. diseases: 373; N. variants: 38
Disease: nervous system disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027765
Disease: nervous system disorder
nervous system disorder 		0.320 GeneticVariation group BEFREE Given recent reports of Kv2.1 dysregulation in neurological disorders, it is possible that alterations in the functional interaction between DAT and Kv2.1 affect dopamine neuron activity. 30824538 2019
CUI: C0027765
Disease: nervous system disorder
nervous system disorder 		0.320 GeneticVariation group BEFREE The coding region of the DAT gene, SLC6A3, is well conserved, but non-coding regions are more variable, most notably a variable number of tandem repeats (VNTR) polymorphism in the 3' untranslated region, which has been studied in a number of dopamine-related neurological disorders, including Parkinson's disease (PD). 16041244 2005
CUI: C0027765
Disease: nervous system disorder
nervous system disorder 		0.320 Biomarker group CTD_human Current research on methamphetamine-induced neurotoxicity: animal models of monoamine disruption. 12890883 2003