Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder
0.540 Biomarker disease BEFREE Dopamine transporter gene (DAT1) has been implicated in attention deficits. 28757070 2017
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder
0.540 AlteredExpression disease BEFREE In conclusion, by regulation of glucocorticoid receptor, GR agonist can decrease DAT expression, resulting in the increase of DA and NE levels in brain that ameliorate hyperactivity and attention deficit in ADHD rats. 28458039 2017
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder
0.540 Biomarker disease MGD Genetic targeting of the amphetamine and methylphenidate-sensitive dopamine transporter: on the path to an animal model of attention-deficit hyperactivity disorder. 24332984 2014
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder
0.540 Biomarker disease MGD The rare DAT coding variant Val559 perturbs DA neuron function, changes behavior, and alters in vivo responses to psychostimulants. 25331903 2014
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder
0.540 Biomarker disease MGD Loss of striatal cannabinoid CB1 receptor function in attention-deficit / hyperactivity disorder mice with point-mutation of the dopamine transporter. 22034972 2011
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder
0.540 Biomarker disease CTD_human Loss of striatal cannabinoid CB1 receptor function in attention-deficit / hyperactivity disorder mice with point-mutation of the dopamine transporter. 22034972 2011
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder
0.540 Biomarker disease CTD_human Association of ADHD, tics, and anxiety with dopamine transporter (DAT1) genotype in autism spectrum disorder. 19120712 2008
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder
0.540 Biomarker disease MGD Sequential super-stereotypy of an instinctive fixed action pattern in hyper-dopaminergic mutant mice: a model of obsessive compulsive disorder and Tourette's. 15710042 2005
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder
0.540 Biomarker disease CTD_human Polymorphisms of the dopamine transporter gene: influence on response to methylphenidate in attention deficit-hyperactivity disorder. 15059031 2004
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder
0.540 GeneticVariation disease BEFREE This suggests that the dopamine transporter genotype influences the attention deficits measured by T.O.V.A. 14584093 2003
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder
0.540 Biomarker disease CTD_human Differential psychostimulant-induced activation of neural circuits in dopamine transporter knockout and wild type mice. 12699766 2003
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder
0.540 Biomarker disease MGD Motor behaviour deficits and their histopathological and functional correlates in the nigrostriatal system of dopamine transporter knockout mice. 12617953 2003
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder
0.540 Biomarker disease MGD Hyperactivity and impaired response habituation in hyperdopaminergic mice. 11172062 2001
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder
0.540 Biomarker disease MGD Differential regulation of tyrosine hydroxylase in the basal ganglia of mice lacking the dopamine transporter. 10564358 1999
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder
0.540 Biomarker disease MGD Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. 9888856 1999
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder
0.540 Biomarker disease MGD Profound neuronal plasticity in response to inactivation of the dopamine transporter. 9520487 1998
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder
0.540 Biomarker disease MGD Anterior pituitary hypoplasia and dwarfism in mice lacking the dopamine transporter. 9247269 1997
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder
0.540 Biomarker disease MGD Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. 8628395 1996
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder
0.540 GeneticVariation disease BEFREE Association of attention-deficit disorder and the dopamine transporter gene. 7717410 1995