SLC6A3, solute carrier family 6 member 3, 6531

N. diseases: 373; N. variants: 38
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0851578
Disease: Sleep Disorders
Sleep Disorders
0.320 Biomarker group CTD_human Dopaminergic role in regulating neurophysiological markers of sleep homeostasis in humans. 24403155 2014
CUI: C0851578
Disease: Sleep Disorders
Sleep Disorders
0.320 Biomarker group BEFREE Our study failed to demonstrate a clear correlation between sleep disorders and DAT densities in MJD patients, hence suggesting that extrastriatal and non-presynaptic dopamine pathways could be implicated in MJD-related sleep disorders. 23137414 2013
CUI: C0851578
Disease: Sleep Disorders
Sleep Disorders
0.320 GeneticVariation group BEFREE Direct associations were identified between the dopamine receptor 3 (DRD3) BalI polymorphism and depression; the dopamine receptor 1 (DRD1) and dopamine transporter gene 3' VNTR polymorphisms and aberrant motor behavior; the DRD4 VNTR and sleep disturbances; and the SERT gene VNTR 5HTTLPR and apathy items. 20685009 2012