SLC6A4, solute carrier family 6 member 4, 6532

N. diseases: 440; N. variants: 28
Disease: Depression, Bipolar ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005587
Disease: Depression, Bipolar
Depression, Bipolar 		0.520 Biomarker disease CTD_human Serotonin transporter linked promoter (polymorphism) in the serotonin transporter gene may be associated with antidepressant-induced mania in bipolar disorder. 16395126 2006
CUI: C0005587
Disease: Depression, Bipolar
Depression, Bipolar 		0.520 Biomarker disease CTD_human Catechol o-methyltransferase, serotonin transporter, and tryptophan hydroxylase gene polymorphisms in bipolar disorder patients with and without comorbid panic disorder. 11772685 2002
CUI: C0005587
Disease: Depression, Bipolar
Depression, Bipolar 		0.520 Biomarker disease PSYGENET The serotonin transporter (5-HTT) is the selective site of action of most proserotonergic compounds used to treat bipolar depression. 11386982 2001
CUI: C0005587
Disease: Depression, Bipolar
Depression, Bipolar 		0.520 Biomarker disease BEFREE The serotonin transporter (5-HTT) is the selective site of action of most proserotonergic compounds used to treat bipolar depression. 11386982 2001
CUI: C0005587
Disease: Depression, Bipolar
Depression, Bipolar 		0.520 Biomarker disease BEFREE The aim of the present study was to investigate for the presence of linkage disequilibrium between SLC6A4 and BP disorder. 10898918 2000
CUI: C0005587
Disease: Depression, Bipolar
Depression, Bipolar 		0.520 Biomarker disease PSYGENET The serotonin transporter (5HTT) gene appears to be of particular interest as 5HTT is the selective site of action of selective serotonin reuptake inhibitors (SSRIs) that successfully treat bipolar depression (BP). 10898918 2000