SLC6A4, solute carrier family 6 member 4, 6532

N. diseases: 440; N. variants: 28
Disease: Severe depression ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0588008
Disease: Severe depression
Severe depression 		0.310 GeneticVariation disease BEFREE Our findings showed an association between low activity alleles of SLC6A4 gene and fluoxetine nonresponse in patients with severe depression. 30520759 2019
CUI: C0588008
Disease: Severe depression
Severe depression 		0.310 Biomarker disease PSYGENET The 5-HTTLPR and 13 additional markers across the serotonin transporter gene were genotyped in 795 adults with moderate-to-severe depression treated with escitalopram or nortriptyline in the Genome Based Therapeutic Drugs for Depression (GENDEP) project. 19567893 2009