SLC11A1, solute carrier family 11 member 1, 6556

N. diseases: 141; N. variants: 14
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.340 GeneticVariation disease BEFREE We studied markers in the genes for NRAMP1 and two mutations in the interferon-gamma receptor in relation to inflammatory bowel disease (IBD) in the following groups: 270 healthy individuals, 74 patients with Crohn's disease, 72 patients with ulcerative colitis, and 40 patients with primary sclerosing cholangitis. 10207725 1999
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.340 Biomarker disease CTD_human The -237C-->T promoter polymorphism of the SLC11A1 gene is associated with a protective effect in relation to inflammatory bowel disease in the South African population. 16059695 2006
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.340 GeneticVariation disease BEFREE For SLC11A1, alleles 1 and 2 were significant (P < 0.05) for UC, but only allele 3 was significant (P < 0.05) for CD. 18340647 2008
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.340 GeneticVariation disease BEFREE five hundred and seven Crohn's disease (CD) patients, 474 ulcerative colitis (UC) patients, and 569 healthy controls were genotyped for SLC11A1 1730G>A and SLC11A1 469+14G>C using pre-designed TaqMan SNP assays. 21128323 2010
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.340 GeneticVariation disease BEFREE No significant association between allele 2 frequency of NRAMP1 and susceptibility to UC/CD was detected in overall population (all p > 0.05). 27019053 2016