Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Diabetes Mellitus, Insulin-Dependent
0.350 GeneticVariation disease BEFREE Evidence of association with type 1 diabetes in the SLC11A1 gene region. 21524304 2011
Diabetes Mellitus, Insulin-Dependent
0.350 GeneticVariation disease BEFREE Since MAP persists within macrophages and it is also processed by dendritic cells, further studies are necessary to evaluate if mutant forms of SLC11A1 alter the processing or presentation of MAP antigens triggering thereby an autoimmune response in T1DM patients. 19768110 2009
Diabetes Mellitus, Insulin-Dependent
0.350 Biomarker disease CTD_human Iron and infection: effects of host iron status and the iron-regulatory genes haptoglobin and NRAMP1 (SLC11A1) on host-pathogen interactions in tuberculosis and HIV. 16597321 2006
Diabetes Mellitus, Insulin-Dependent
0.350 GeneticVariation disease BEFREE Because allele 2 was shown to be associated with low expression of SLC11A1 and protection against another autoimmune disease, rheumatoid arthritis, the negative association of allele 2 with autoimmune type 1 diabetes in the present study suggests that a less active immune system in subjects with allele 2 may protect individuals from autoimmune diseases. 15877293 2005
Diabetes Mellitus, Insulin-Dependent
0.350 GeneticVariation disease BEFREE These findings suggest that the novel promoter polymorphism of SLC11A1 influences the susceptibility to type 1 diabetes in Japanese subjects. 14989712 2004
Diabetes Mellitus, Insulin-Dependent
0.350 Biomarker disease BEFREE The association study of the cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) gene, located near the NRAMP1 gene, and type 1 diabetes showed that the CTLA-4 gene significantly contributed to the development of type 1 diabetes, whereas NRAMP1 had an additional effect on the onset of type 1 diabetes in the young population. 12136340 2002