|
Non-Small Cell Lung Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Retrospectively, immunohistochemistry was performed to study stromal protein expression of both CD34 and SMA in 304 NSCLC patients with pTNM stage I-III disease.
|
31760702 |
2020 |
|
Idiopathic Membranous Glomerulonephritis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
<b>Conclusion</b>: This study of two cohorts from different regions of China indicate that specific <i>PLA2R1</i> polymorphisms are associated with IMN and SMN.
|
31532353 |
2020 |
|
Idiopathic pulmonary arterial hypertension
|
0.010 |
Biomarker
|
disease |
BEFREE |
The right ventricular systolic pressure (RVSP), right ventricle hypertrophy index (RVHI), percentage of medial wall thickness (%MT), α-SMA, Ki-67 and TUNEL staining were performed to evaluate the development of PAH.
|
31837334 |
2020 |
|
Brain Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
OBJECTIVESupplementary motor area (SMA) syndrome is defined as temporary paralysis after the resection of brain tumor localized in the SMA.
|
30738403 |
2019 |
|
Malignant neoplasm of breast
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Here, we investigated the effect of TP53 on α‑SMA expression in breast cancer cells.
|
30535478 |
2019 |
|
Craniosynostosis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The associations were assessed between α‑SMA expression and the clinical features of CRS.
|
31322276 |
2019 |
|
Empyema
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Myocardin, α-SMA, calponin, and smooth muscle myosin were notably upregulated in the thickened pleura of carbon black/bleomycin and empyema mouse models of fibrosing pleural injury.
|
30605348 |
2019 |
|
Fenestration (morphologic abnormality)
|
0.010 |
Biomarker
|
disease |
BEFREE |
For the SMA (N.=341) fenestrations were used in 169 (49.6%) and branches in 172 (50.4%).
|
29943962 |
2019 |
|
Polyostotic fibrous dysplasia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Treatment with PFD significantly reduced ConA-induced expression of type II and IV collagens, α-SMA mRNA expression, and HP content and decreased inflammatory cells infiltration in hepatic tissues.
|
31639402 |
2019 |
|
Female Genital Diseases
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Our results showed that ADSCs from omentum of ovarian cancer patients，no matter whether metastasis or not, expressed higher levels of α-SMA than ADSCs from patients with benign gynecologic disease.
|
31046126 |
2019 |
|
Membranous glomerulonephritis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Subgroup analysis by treatment strategies, assay methods, ethnicity, gender, renal function, the approach of ruling out SMN, and the ratio of patients with nephrotic-range proteinuria at baseline showed no significant association between these factors with the prognostic value of sPLA2R-ab for PMN patients.
|
31533641 |
2019 |
|
Hepatitis A
|
0.010 |
Biomarker
|
disease |
BEFREE |
Furthermore, TLR4 overexpression induced by DEN was decreased by Baishouwu extract, leading to the markedly down-regulated levels of MyD88, TRAF6, NF-κB p65, TGF-β1 and α-SMA in hepatitis, cirrhosis, and hepatocarcinoma.
|
31068809 |
2019 |
|
Icterus
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
Lower area percent expression of α-SMA correlated with increased probability of jaundice clearance after KPE (P < 0.001).
|
30381493 |
2019 |
|
Keloid
|
0.010 |
Biomarker
|
disease |
BEFREE |
The reconstructed keloid showed increased contraction, dermal thickness (trend) and α-SMA+ staining, but co-culture with monocytes did not further enhance the keloid phenotype.
|
31187196 |
2019 |
|
Fibroid Tumor
|
0.010 |
Biomarker
|
disease |
BEFREE |
Histopathology sections from the nail matrix biopsy specimen showed a dermal proliferation of bland appearing spindle shaped cells with elongated, blunt ended nuclei (SMA and caldesmon positive), arranged in fascicles, which is typical of leiomyomas.
|
31141855 |
2019 |
|
Leukopenia
|
0.010 |
Biomarker
|
disease |
BEFREE |
The results of our study revealed that during the first week, there were significant elevations of fibrin, tissue factor expressions, and prothrombin time (PT) coupled with neutropenia without significant changes in liver fibrosis markers such as TGF-β, α-SMA and collagen deposition.
|
31158377 |
2019 |
|
melanoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Herein, by scrutinizing the expression of α-SMA and PD-L1 in melanoma and CRC tissues, we found that CAFs was positive correlated with PD-L1 expression.
|
30873585 |
2019 |
|
Neutropenia
|
0.010 |
Biomarker
|
disease |
BEFREE |
The results of our study revealed that during the first week, there were significant elevations of fibrin, tissue factor expressions, and prothrombin time (PT) coupled with neutropenia without significant changes in liver fibrosis markers such as TGF-β, α-SMA and collagen deposition.
|
31158377 |
2019 |
|
Scoliosis, unspecified
|
0.010 |
Biomarker
|
disease |
BEFREE |
Due to the clinical features of SMA, the application of the ASO by lumbar puncture can be challenging in symptomatic patients considering the frequently observed scoliosis, previous spine fusion surgeries, joint contractures, and respiratory insufficiency.
|
30460449 |
2019 |
|
Chronic sinusitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Epithelial‑mesenchymal transition in chronic rhinosinusitis (CRS) and the prognostic value of α‑SMA in postoperative outcomes of patients with CRS.
|
31322276 |
2019 |
|
Disuse osteoporosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Retrospective chart review of IV BP for treatment of disuse osteoporosis and low BMD in children with SMA at a tertiary pediatric center from 2010 to 2018 RESULTS: Eight patients (50% female; 75% SMA type 1; median age at first infusion 6.7 years) receiving a total of 39 infusions (54% pamidronate, 46% zoledronic acid) were included in this report.
|
31788718 |
2019 |
|
Alpers Syndrome (disorder)
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Adult forms of SMA are associated with selective grey matter degeneration in the spinal cord with preserved white matter integrity.
|
30522974 |
2019 |
|
Multiple Acyl Coenzyme A Dehydrogenase Deficiency
|
0.010 |
Biomarker
|
disease |
BEFREE |
Immunohistochemical staining demonstrated cells labeled with VIM (+), CD68PGM1 (+), CD34 (-), Actin (-), PCK (-), EMA (-), Desmin (-), SMA (-), S-100 (-), P63 (-), ALK-1 (-), beta-catenia (+), and KI67 (+).
|
31169683 |
2019 |
|
Malignant Childhood Neoplasm
|
0.010 |
Biomarker
|
disease |
BEFREE |
The previously observed inverse relationship between LTL and thyroid SMN risk in survivors of childhood cancer may be related to alternative molecular mechanisms and warrants further study.
|
30377209 |
2019 |
|
Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Prolonged administration of RSV significantly suppressed high-grade biliary neoplasia (P = 0.008), attenuated upregulation of hyperplasia and fibrogenesis-related genes (Tgfb, α-SMA and CK7), and decreased the elevated oxidative DNA damage.
|
31628937 |
2019 |