SMS, spermine synthase, 6611

N. diseases: 263; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Amputated structure (morphologic abnormality)
0.010 GeneticVariation phenotype BEFREE Among the 121 case matched pairs of patients, those with SPS vs. DES were not significantly more likely to develop TLR >50% (31% vs. 27%, p = .34), or stent occlusion (13% vs. 12%, p = .85 - secondary patency rate 87% vs. 88%), have a major amputation (10% vs. 6%, p = .16), require re-intervention (14% vs. 9%, p = .12), or die (7% vs.4%, p = .31). 31500990 2019
CUI: C0346627
Disease: Intestinal Cancer
Intestinal Cancer
0.010 Biomarker disease BEFREE The purpose of the present study was to evaluate the potential utility of GP endorsement letters or SMS in the context of facilitating bowel cancer screening in previous nonparticipants and to identify mechanisms underlying responses. 30855076 2019
CUI: C0424166
Disease: Social Anxiety
Social Anxiety
0.010 Biomarker disease BEFREE Social anxiety was assessed using short forms of the Social Phobia Scale (SPS-6) and Social Interaction Anxiety Scale (SIAS-6). 31675602 2019
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
0.010 Biomarker phenotype BEFREE The original SRS target volume overlapped with a median of 69.6% of the recurrent tumor. 30029965 2019
CUI: C0687132
Disease: heavy drinking
heavy drinking
0.010 Biomarker disease BEFREE Gender race/ethnicity, marital status, mode of transport used to purchase alcohol, perceptions of alcohol availability and exposure to alcohol promotions and advertising through SMS and free offers when buying alcohol all impacted heavy drinking. 31076000 2019
CUI: C0740418
Disease: Chronic back pain
Chronic back pain
0.010 GeneticVariation phenotype BEFREE Poor self-image and mental health scores in SRS-22r were identified as risk factors for chronic back pain. 30817729 2019
CUI: C0741585
Disease: BODY ACHE
BODY ACHE
0.010 Biomarker phenotype BEFREE The Sat-2y score was strongly correlated with the SRS-22R self-image (SI)/appearance subdomain (r = 0.64), followed by moderate correlation with subdomains related to standing (r = 0.53), body pain (r = 0.49-0.55), and function (r = 0.41-0.55) at 2 years. 31075761 2019
CUI: C0751606
Disease: Adult Acute Lymphocytic Leukemia
Adult Acute Lymphocytic Leukemia
0.010 Biomarker disease BEFREE The SRS-30 proved to provide valid HRQoL scores for all adult patients with degenerative spinal disorders. 31106613 2019
CUI: C0860603
Disease: Anxiety symptoms
Anxiety symptoms
0.010 AlteredExpression phenotype BEFREE Overall, the results reveal time-dependent progression in development of anxiety symptoms and molecular impairments in gene expression for CRH and NPY systems in LC and mediobasal hypothalamus by SPS. 30878321 2019
CUI: C1285162
Disease: Degenerative disorder
Degenerative disorder
0.010 Biomarker group BEFREE The Scoliosis Research Society (SRS-30) questionnaire proved valid in measuring health-related quality of life (HRQoL) in adult patients with spinal deformity or degenerative disease. 31106613 2019
PREMATURE CHROMATID SEPARATION TRAIT
0.010 AlteredExpression disease BEFREE SF36-PCS significantly correlated with the muscular volume; SRS and Oswestry disability index correlated with the erectors spinae volume (p < 0.05). 31811390 2019
CUI: C3489532
Disease: Cone-Rod Dystrophy 2
Cone-Rod Dystrophy 2
0.010 Biomarker disease BEFREE Ferroptosis inhibitor SRS 16-86 attenuates ferroptosis and promotes functional recovery in contusion spinal cord injury. 30352209 2019
CUI: C3539878
Disease: Triple Negative Breast Neoplasms
Triple Negative Breast Neoplasms
0.010 Biomarker disease BEFREE An increase in plasma DAS, a catabolic product of spermine mediated through SMS, was observed in the TNBC subtype of breast cancer. 31503278 2019
CUI: C3890602
Disease: Bodily Pain
Bodily Pain
0.010 Biomarker phenotype BEFREE The Sat-2y score was strongly correlated with the SRS-22R self-image (SI)/appearance subdomain (r = 0.64), followed by moderate correlation with subdomains related to standing (r = 0.53), body pain (r = 0.49-0.55), and function (r = 0.41-0.55) at 2 years. 31075761 2019
Malignant neoplasm of colon and/or rectum
0.010 AlteredExpression disease BEFREE In the present study, a sulfated glucuronorhamnoxylan polysaccharide (named SPS-CF) purified from a green alga Capsosiphon fulvescens was evaluated for its anti-cancer activity in vitro and in vivo against colorectal cancer. 30521889 2019
CUI: C4722518
Disease: Triple-Negative Breast Carcinoma
Triple-Negative Breast Carcinoma
0.010 Biomarker disease BEFREE An increase in plasma DAS, a catabolic product of spermine mediated through SMS, was observed in the TNBC subtype of breast cancer. 31503278 2019
CUI: C0001430
Disease: Adenoma
Adenoma
0.010 Biomarker group BEFREE From July 2003 to December 2013, there were 41 cases of recurrent or residual nonfunctioning pituitary macroadenoma partially treated with gamma knife radiosurgery (GKRS) because the adenoma obscured part of the optic apparatus on planning SRS MR imaging. 29948768 2018
CUI: C0007282
Disease: Carotid Stenosis
Carotid Stenosis
0.010 Biomarker disease BEFREE Intracranial carotid stenosis or occlusion after SRS is an extraordinarily rare event. 29097132 2018
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.010 Biomarker disease BEFREE A spiritually-based SMS text messaging intervention could be a culturally-appropriate and cost-effective method of promoting cervical cancer early detection information to church-attending African-American women. 30300091 2018
CUI: C0020502
Disease: Hyperparathyroidism
Hyperparathyroidism
0.010 Biomarker disease BEFREE Compared with SPS, CPS may be safer for the treatment of hyperkalemia in pre-dialysis patients, because it did not induce hyperparathyroidism or volume overload. 28421299 2018
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.010 Biomarker group BEFREE We aimed to describe our experience of using the Medical Research Council (MRC) Framework on complex interventions to develop and evaluate an adherence support intervention for high blood pressure delivered by SMS text message. 29361934 2018
CUI: C0020635
Disease: Hypopituitarism
Hypopituitarism
0.010 Biomarker disease BEFREE Robotic SRS is a safe and effective treatment for acromegaly: radiation-induced visual complications and hypopituitarism is rare. 29429125 2018
CUI: C0021125
Disease: Impulsive Behavior
Impulsive Behavior
0.010 Biomarker phenotype BEFREE There were strong correlations between FLV Hyperactivity and Cognitive problems/Inattention scores and ADHD-SRS scores of Impulsivity/Hyperactivity ( r = .90) and Inattention ( r = .68) and also strong correlations between FLV Opposition score and the CBCL scores of Aggressive behavior ( r = .84) and Rule-breaking behavior ( r = .66). 29562852 2018
CUI: C0030201
Disease: Pain, Postoperative
Pain, Postoperative
0.010 GeneticVariation phenotype BEFREE Patients with a Cobb angle of <50 degrees displayed significantly milder postoperative pain (4.7 vs. 4.3, p = 0.031), with no remarkable differences in other SRS-22 domain scores. 28943143 2018
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.010 Biomarker disease BEFREE This study aimed to investigate the relationship between Scoliosis Research Society-22 (SRS-22) domains and satisfaction with management in patients who underwent surgical correction for ankylosing spondylitis kyphosis. 29316959 2018