SNCB, synuclein beta, 6620

N. diseases: 60; N. variants: 4
Disease: Mental deterioration ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.020 Biomarker phenotype BEFREE The presence of RBD in PD is associated with faster motor progression in patients with greater synuclein and dopaminergic pathology, and with higher risk of cognitive decline in patients with greater synuclein and amyloid pathology. 30089615 2018
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.020 Biomarker phenotype BEFREE CSF A<i>β</i>, <i>α</i>-synuclein, and neurogranin concentrations are related to cortical metabolism and cognitive decline. 29046879 2017