SNCB, synuclein beta, 6620

N. diseases: 60; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0338656
Disease: Impaired cognition
Impaired cognition
0.030 Biomarker disease BEFREE The presence of RBD in PD is associated with faster motor progression in patients with greater synuclein and dopaminergic pathology, and with higher risk of cognitive decline in patients with greater synuclein and amyloid pathology. 30089615 2018
CUI: C0338656
Disease: Impaired cognition
Impaired cognition
0.030 Biomarker disease BEFREE Synaptic dysfunction due to A<i>β</i> and <i>α</i>-synuclein dysmetabolism may be central in the evolution of cognitive impairment in Parkinson's disease. 29046879 2017
CUI: C0338656
Disease: Impaired cognition
Impaired cognition
0.030 Biomarker disease BEFREE Previous studies have shown altered synuclein, increased oxidative stress damage and increased oxidative stress responses in patients with sporadic Parkinson's disease (PD) without cognitive impairment. 20232069 2010