Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder)
0.900 Biomarker disease MGD Alpha-synuclein A30P point-mutation generates age-dependent nigrostriatal deficiency in mice. 18622040 2008
PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder)
0.900 GeneticVariation disease UNIPROT Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. 9197268 1997
PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder)
0.900 GeneticVariation disease UNIPROT The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia. 14755719 2004
PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder)
0.900 GeneticVariation disease UNIPROT Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. 9462735 1998
PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder)
0.900 GeneticVariation disease UNIPROT A novel α-synuclein missense mutation in Parkinson disease. 23427326 2013
PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder)
0.900 GeneticVariation disease UNIPROT The H50Q mutation enhances α-synuclein aggregation, secretion, and toxicity. 24936070 2014
PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder)
0.900 Biomarker disease GENOMICS_ENGLAND
PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder)
0.900 GeneticVariation disease UNIPROT Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease. 23457019 2013
PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder)
0.900 CausalMutation disease CLINVAR
PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder)
0.900 Biomarker disease MGD Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system. 10707987 2000
PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder)
0.900 Biomarker disease CTD_human
PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder)
0.900 GeneticVariation disease UNIPROT Molecular determinants of α-synuclein mutants' oligomerization and membrane interactions. 25561023 2015
PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder)
0.900 Biomarker disease GENOMICS_ENGLAND